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Synthesis and Study of Luminescent, Anti-Mao, and Antioxidant Properties of (2E)-3-Aryl-1-(4-alkoxyphenyl)prop-2-ene-1-ones and Their Pyrazoline Derivatives

By condensation of 1-(4-alkoxyphenyl)ethanones with aromatic aldehydes in the presence of sodium hydroxide in an aqueous-ethanol solution, (2 E )-3-aryl-1-(4-alkoxyphenyl)prop-2-ene-1-ones were obtained. Cyclization of these latter with phenylhydrazine in an acidic medium leads to the corresponding...

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Published in:Russian journal of general chemistry 2024, Vol.94 (11), p.2847-2858
Main Authors: Hakobyan, N. Z., Isakhanyan, A. U., Grigoryan, G. S., Mkhitaryan, R. P., Sargsyan, H. R., Grigoryan, A. S., Pahutyan, N. H., Pogosyan, A. E., Аrajyan, G. М., Gasparyan, H. V., Muradyan, R. Y., Panosyan, Н. A., Israelyan, S. G., Harutyunyan, A. A.
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container_end_page 2858
container_issue 11
container_start_page 2847
container_title Russian journal of general chemistry
container_volume 94
creator Hakobyan, N. Z.
Isakhanyan, A. U.
Grigoryan, G. S.
Mkhitaryan, R. P.
Sargsyan, H. R.
Grigoryan, A. S.
Pahutyan, N. H.
Pogosyan, A. E.
Аrajyan, G. М.
Gasparyan, H. V.
Muradyan, R. Y.
Panosyan, Н. A.
Israelyan, S. G.
Harutyunyan, A. A.
description By condensation of 1-(4-alkoxyphenyl)ethanones with aromatic aldehydes in the presence of sodium hydroxide in an aqueous-ethanol solution, (2 E )-3-aryl-1-(4-alkoxyphenyl)prop-2-ene-1-ones were obtained. Cyclization of these latter with phenylhydrazine in an acidic medium leads to the corresponding 5-aryl-3-(4-alkoxyphenyl)-1-phenyl-4,5-dihydro-1 H -pyrazoles. The luminescent, antimonoamine oxidase, and antioxidant properties of the compounds obtained were studied.
doi_str_mv 10.1134/S1070363224110057
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recordid cdi_proquest_journals_3146496204
source Springer Nature
subjects Acidic oxides
Aldehydes
Antioxidants
Aromatic compounds
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Ethanol
Sodium hydroxide
title Synthesis and Study of Luminescent, Anti-Mao, and Antioxidant Properties of (2E)-3-Aryl-1-(4-alkoxyphenyl)prop-2-ene-1-ones and Their Pyrazoline Derivatives
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