Primary Pulmonary Small B-Cell Non-Hodgkin Lymphoma -Case Presentation

Primary pulmonary non-Hodgkin lymphoma is a rare entity, accounting for 3-4% of extranodal non-Hodgkin lymphomas. Indolent primary pulmonary non-Hodgkin lymphomas are the most frequent types, with the MALT subtype representing majority of cases. Other indolent subtypes of B-cell primary pulmonary ly...

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Bibliographic Details
Published in:Ars medica tomitana 2020-05, Vol.26 (2), p.80-84
Main Authors: Andreea-Georgiana, Stoica, Irina, Tica, Sabina-Livia, Ciocodei, Anca-Florentina, Mitroi, Costel, Brînzan, Antonela-Anca, Nicolau, Camelia, Cozaru Georgeta, Mariana, Aschie, Maria, Ghinea Mihaela
Format: Article
Language:English
Subjects:
lung
Lymphoma
non-Hodgkin lymphoma
small B-cell lymphoma
Tomography
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Summary:Primary pulmonary non-Hodgkin lymphoma is a rare entity, accounting for 3-4% of extranodal non-Hodgkin lymphomas. Indolent primary pulmonary non-Hodgkin lymphomas are the most frequent types, with the MALT subtype representing majority of cases. Other indolent subtypes of B-cell primary pulmonary lymphomas are rare. We present the case of a 56-year-old patient, non-smoker, who presents for pain in the right hemithorax, worsened by deep inhales. Pulmonary X-ray showed a right paramediastinal superior and medial lobe homogenous opacity with faded contour. Thoracic computed tomography scan described a dense right superior mediastino-pulmonary tumoral mass, the absence of hilar or mediastinal adenopathies. In this context, an ultrasound-guided transbronchial needle aspiration was performed. Histopathology and immunohistochemistry confirmed the diagnosis of primary pulmonary small B-cell non-Hodgkin lymphoma. After 6 chemotherapy cycles, from a clinical and imagistic (thoracic CT scan) point of view, the response was favourable. Positron emission tomography (PET/CT) aspect indicated a complete metabolic response to treatment.
ISSN:1841-4036
1223-9666
1841-4036
DOI:10.2478/arsm-2020-0016