Inflammatory and Imaging-based Predictors of Atrial Fibrillation Recurrence after Pulmonary Vein Isolation Using Electroanatomical Mapping – the INFLAMAP Study

Atrial fibrillation (AF) is the most frequent form of supraventricular arrhythmia in medical practice. It is characterized by chaotic electrical activity in the atria, which often leads to irregular and fast ventricular contractions. Pulmonary veins (PV) play an essential part in the genesis of AF....

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Bibliographic Details
Published in:Journal of Interdisciplinary Medicine 2018-03, Vol.3 (1), p.10-15
Main Authors: Korodi, Szilamér, Benedek, Theodora, Bordi, Lehel, Kovács, István, Rat, Nora, Márton, Emese, Rațiu, Mihaela, Benedek, Imre
Format: Article
Language:English
Subjects:
atrial fibrillation
atrial volume
epicardial adipose tissue
inflammatory biomarkers
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Summary:Atrial fibrillation (AF) is the most frequent form of supraventricular arrhythmia in medical practice. It is characterized by chaotic electrical activity in the atria, which often leads to irregular and fast ventricular contractions. Pulmonary veins (PV) play an essential part in the genesis of AF. There are a series of risk factors that trigger the development and recurrence of AF after PV isolation. Despite advanced medical technology, the success rate of AF ablation is not satisfactory. The purpose of this study is to assess the preprocedural imaging and serum biomarkers linked to an increased recurrence of AF after PV isolation. The primary endpoint is represented by AF recurrence after PV isolation. In addition, the rate of cardiovascular death and the rate of major adverse cardiovascular events will be assessed in relation to the enlargement of the left atrium and the volume of epicardial adipose tissue surrounding the heart.
ISSN:2501-8132
2501-5974
2501-8132
DOI:10.2478/jim-2018-0007