Primary epithelioid angiosarcoma of the mandibular gingiva: diagnostic pitfalls, about an unusual entity

Primary angiosarcoma of the oral cavity is a rare malignant vascular neoplasm variably recapitulating endothelial cells and is generally associated with a worse prognosis. The epithelioid subtype is even uncommon in this localization. To our knowledge, only seven cases of primary oral epithelioid an...

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Bibliographic Details
Published in:Journal of surgical case reports 2024-05, Vol.2024 (5), p.rjae323
Main Authors: El ouazzani, Hafsa, Hamidi, Olaya, Habimana, Alain, Dani, Bouchra, Boulaadas, M, Zouaidia, Fouad, Cherradi, Nadia
Format: Article
Language:English
Subjects:
Cancer
Case reports
Chemotherapy
Cytokeratin
Localization
Melanoma
Metastasis
Morphology
Pathology
Sarcoma
Squamous cell carcinoma
Tumors
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Summary:Primary angiosarcoma of the oral cavity is a rare malignant vascular neoplasm variably recapitulating endothelial cells and is generally associated with a worse prognosis. The epithelioid subtype is even uncommon in this localization. To our knowledge, only seven cases of primary oral epithelioid angiosarcoma have been reported until 2021. This histopathological variant is characterized by solid and sheet-like growth patterns that may be misinterpreted as other lesions with epithelioid cells. Herein, we present a new case of primary epithelioid angiosarcoma of the mandibular gingiva to discuss histopathological differential diagnoses and potential diagnostic pitfalls.
ISSN:2042-8812
2042-8812
DOI:10.1093/jscr/rjae323