Macroscopic and microscopic characterisation of colitis in a mice model of inflammatory bowel disease and its application to nutritional therapeutics

(ProQuest: ... denotes non-US-ASCII text omitted.) The mdr1a-/- mice lack the multiple drug resistance gene for P-glycoprotein, normally expressed in multiple tissues including intestinal epithelial cells(1), and develop a spontaneous colitis.

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Bibliographic Details
Published in:Proceedings of the Nutrition Society 2010, Vol.69 (OCE3), Article E263
Main Authors: Pérez-Bosque, A., Maijó, M., Miró, L., Polo, J., Weaver, E., Crenshaw, J., Russell, L., Campbell, J., Moretó, M.
Format: Article
Language:English
Subjects:
Colon
Drug resistance
Inflammatory bowel disease
Medical research
Rodents
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Description
Summary:(ProQuest: ... denotes non-US-ASCII text omitted.) The mdr1a-/- mice lack the multiple drug resistance gene for P-glycoprotein, normally expressed in multiple tissues including intestinal epithelial cells(1), and develop a spontaneous colitis.
ISSN:0029-6651
1475-2719
DOI:10.1017/S0029665110000522