Important issues in the drug treatment of schizophrenia

The large body of research demonstrating the effectiveness of antipsychotic drugs in the treatment of acute schizophrenia is selectively reviewed. Research evidence relevant to the following issues is assessed; indications for selective treatment; characteristics of drug responders and nonresponders...

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Bibliographic Details
Published in:Schizophrenia bulletin 1980, Vol.6 (1), p.70-87
Main Authors: Davis, J M, Schaffer, C B, Killian, G A, Kinard, C, Chan, C
Format: Article
Language:English
Subjects:
Antipsychotic Agents - adverse effects
Antipsychotic Agents - therapeutic use
Client Characteristics
Dose-Response Relationship, Drug
Drug Dosages
Drug Therapy
Follow-Up Studies
Human
Humans
Literature Review
Neuroleptic Drugs
Phenothiazines
Psychiatric Status Rating Scales
Psychotherapy
Recurrence
Relapse (Disorders)
Schizophrenia
Schizophrenia - drug therapy
Schizophrenic Psychology
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Description
Summary:The large body of research demonstrating the effectiveness of antipsychotic drugs in the treatment of acute schizophrenia is selectively reviewed. Research evidence relevant to the following issues is assessed; indications for selective treatment; characteristics of drug responders and nonresponders; indications for high dosage phenothiazine treatment; indications for maintenance therapy; benefits and risks of antipsychotic drugs. Recommendations are made concerning areas of psychopharmacologic research that require further development.
ISSN:0586-7614
1745-1701
DOI:10.1093/schbul/6.1.70