Characterization of a cDNA encoding a protein with limited similarity to [beta]1, 3-N-acetylglucosaminyltransferase

Glycosyltransferases constitute a large group of enzymes that are involved in a wide range of functions in all living organisms. By large-scale sequencing analysis of a human fetal brain cDNA library, we isolated a novel human putative glycosyltransferase gene named β3GnTL1. Its cDNA is 1372 base pa...

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Bibliographic Details
Published in:Molecular biology reports 2004-09, Vol.31 (3), p.171
Main Authors: Zheng, Huarui, Li, Yao, Ji, Chaoneng, Li, Jixi, Zhang, Jiayi, Yin, Gang, Xu, Jian, Ye, Xin, Wu, Maoqing, Zou, Xianqiong, Gu, Shaohua, Xie, Yi, Mao, Yumin
Format: Article
Language:English
Subjects:
Amino acids
Genes
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Summary:Glycosyltransferases constitute a large group of enzymes that are involved in a wide range of functions in all living organisms. By large-scale sequencing analysis of a human fetal brain cDNA library, we isolated a novel human putative glycosyltransferase gene named β3GnTL1. Its cDNA is 1372 base pair in length, encoding a predicted protein with 361 amino acid residues. The human β3GnTL1 is located to chromosome 17q25.3 by comparison of its cDNA with human gemome database. RT-PCR result shows the β3GnTL1 is expressed at various levels in most of tissues examined. Abbreviations:β3GnT -β1, 3-N-acetylglucosaminyltransferase;β4GalT -β1, 4-galactosyltransferase; GTs - glycosyltransferases.[PUBLICATION ABSTRACT]
ISSN:0301-4851
1573-4978
DOI:10.1023/B:MOLE.0000043552.32411.67