Plasma membrane H+-ATPase activity in wild type and mutants ofSaccharomyces cerevisiae treated by some lysosomotropic drugs

ConclusionsThe aminoesters inhibit glucose-stimulated proton extrusion by yeast cells.The inhibitory activity depends on aliphatic carbon chain length.The inhibition of proton extrusion is concentration-dependent.The aminoesters stimulate quinacrine accumulation in vacuoles of yeast cells so they sh...

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Bibliographic Details
Published in:Folia microbiologica 1998-03, Vol.43 (2), p.201-203
Main Authors: Lachowicz, T. M., Krasowska, A., Łuczyński, J., Witek, S.
Format: Article
Language:English
Subjects:
Bacteria
Plasma
Yeasts
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Summary:ConclusionsThe aminoesters inhibit glucose-stimulated proton extrusion by yeast cells.The inhibitory activity depends on aliphatic carbon chain length.The inhibition of proton extrusion is concentration-dependent.The aminoesters stimulate quinacrine accumulation in vacuoles of yeast cells so they should possess affinities for lysosomes.
ISSN:0015-5632
1874-9356
DOI:10.1007/BF02816514