Antifungal fractions and compounds from uncrushed Green Leaves ofAzadirachta indica

Using the groundnut rust disease (causal agentPuccinia arachidis Speg.) as the bioassay system, two limonoids from the neem tree (Azadirachta indica A. Juss.) which evinced antifungal activity, were isolated through extraction, solvent fractionation and HPLC. A polar extract derived through solvent...

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Bibliographic Details
Published in:Phytoparasitica 1997-03, Vol.25 (1), p.33-39
Main Authors: Suresh, G., Narasimhan, N. S., Masilamani, S., Partho, P. D., Gopalakrishnan, Geetha
Format: Article
Language:English
Subjects:
Antifungal activity
Bioassays
Fractionation
Fungi
Fungicides
High-performance liquid chromatography
Liquid chromatography
Neem
Plant diseases
Plant pathology
Rust fungi
Solvent fractionation
Solvents
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Summary:Using the groundnut rust disease (causal agentPuccinia arachidis Speg.) as the bioassay system, two limonoids from the neem tree (Azadirachta indica A. Juss.) which evinced antifungal activity, were isolated through extraction, solvent fractionation and HPLC. A polar extract derived through solvent partitioning reduced the disease intensity considerably. The polar extract and the impure HPLC fractions were more effective than the pure compounds in reducing the pustule numbers and, consequently, the disease severity.
ISSN:0334-2123
1876-7184
DOI:10.1007/BF02981477