Rapid Method for Identification of Interconnections between Functionally and/or Evolutionarily Related Biological Sequences

It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, com...

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Bibliographic Details
Published in:Molecular biology (New York) 2001-11, Vol.35 (6), p.867
Main Authors: Gusev, V D, Nemytikova, L A, Chuzhanova, N A
Format: Article
Language:English
Subjects:
Growth hormones
Online Access:Get full text
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Summary:It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, common structural elements. Knowledge of these interconnections is necessary for further processing of the sequences. We propose a rapid (single scan) method for identification of such interconnections by means of complexity analysis that generalizes the Lempel-Ziv approach. Analysis of a selection of 5"-flanking regions of vertebrate growth hormone genes from EMBL is presented as an example.[PUBLICATION ABSTRACT]
ISSN:0026-8933
1608-3245
DOI:10.1023/A:1013290302922