Topography of digestive enzymes in small intestine and activity of corresponding hydrolases in liver and kidney of adult pigs

Distribution of activities of disaccharidases (saccharase, maltase), amino- and dipeptidases, dipeptidyl peptidase IV (DPP) and alkaline phosphatase along the small intestine and of these hydrolases in liver and kidney, as well as distribution of the digestive enzyme activities between the membrane...

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Bibliographic Details
Published in:Journal of evolutionary biochemistry and physiology 2005-01, Vol.41 (1), p.47-53
Main Authors: Smirnova, E. V., Gordova, L. A., Timofeeva, N. M., Shcherbakov, G. G.
Format: Article
Language:English
Subjects:
Enzymes
Small intestine
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Summary:Distribution of activities of disaccharidases (saccharase, maltase), amino- and dipeptidases, dipeptidyl peptidase IV (DPP) and alkaline phosphatase along the small intestine and of these hydrolases in liver and kidney, as well as distribution of the digestive enzyme activities between the membrane and cytosol fractions of enterocytes is characterized in adult 6-month old pigs. It has been shown that maximum of the studied enzyme activities, except for DPP, takes place in ileum. A higher level of the activities of the soluble form of saccharase, maltase, and aminopeptidase M and a less significant level of the activity of the glycyl-L-leucine dipeptidase soluble form in jejunum and ileum is found than those in rats and monkeys. The obtained data demonstrate the existence of the complex enzyme system in small intestine, liver, and kidney that participate in realization of nutritive and trophic-barrier functions.[PUBLICATION ABSTRACT]
ISSN:0022-0930
1608-3202
DOI:10.1007/s10893-005-0034-2