Synthesis and Antimicrobial Activity of a Silver-Hydroxyapatite Nanocomposite

A silver-hydroxyapatite nanocomposite has been obtained by a colloidal chemical route and subsequent reduction process in H2/Ar atmosphere at 350∘C. This material has been characterized by TEM, XRD, and UV-Visible spectroscopy, showing the silver nanoparticles (∼65 nm) supported onto the HA particle...

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Bibliographic Details
Published in:Journal of nanomaterials 2009-01, Vol.2009 (1)
Main Authors: Díaz, Marcos, Barba, Flora, Miranda, Miriam, Guitián, Francisco, Torrecillas, Ramón, Moya, José S.
Format: Article
Language:English
Subjects:
Antibiotics
Bacteria
E coli
Hospitals
Nanomaterials
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Summary:A silver-hydroxyapatite nanocomposite has been obtained by a colloidal chemical route and subsequent reduction process in H2/Ar atmosphere at 350∘C. This material has been characterized by TEM, XRD, and UV-Visible spectroscopy, showing the silver nanoparticles (∼65 nm) supported onto the HA particles (∼130 nm) surface without a high degree of agglomeration. The bactericidal effect against common Gram-positive and Gram-negative bacteria has been also investigated. The results indicated a high antimicrobial activity for Staphylococcus aureus, Pneumococcus and Escherichia coli, so this material can be a promising antimicrobial biomaterial for implant and reconstructive surgery applications.
ISSN:1687-4110
1687-4129
DOI:10.1155/2009/498505