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Simple and Efficient Method for Synthesis of Bis(indolyl) Methanes with Cu(BF4)2·SiO2 Under Mild Conditions
A simple and efficient synthesis of bis(indolyl) methanes by the reaction of indoles with various carbonyl compounds in the presence of a catalytic amount of cupric fluoroborate [Cu(BF 4 ) 2 ·SiO 2 ] afforded the corresponding bis(indolyl) methanes in excellent yields. The remarkable selectivity und...
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Published in: | Synthetic communications 2010-01, Vol.40 (1), p.29-38 |
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Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | A simple and efficient synthesis of bis(indolyl) methanes by the reaction of indoles with various carbonyl compounds in the presence of a catalytic amount of cupric fluoroborate [Cu(BF
4
)
2
·SiO
2
] afforded the corresponding bis(indolyl) methanes in excellent yields. The remarkable selectivity under mild and neutral conditions and commercially available, inexpensive catalyst are attractive features of this method. |
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ISSN: | 0039-7911 1532-2432 |
DOI: | 10.1080/00397910902916064 |