Marine Fungi Aspergillus sydowii and Trichoderma sp. Catalyze the Hydrolysis of Benzyl Glycidyl Ether

• Published in: Marine biotechnology (New York, N.Y.) N.Y.), 2011-04, Vol.13 (2), p.314-320
• Main Authors: Martins, Mariana Provedel, Mouad, Ana Maria, Boschini, Letícia, Regali Seleghim, Mirna Helena, Sette, Lara Durães, Meleiro Porto, André Luiz
• Format: Article
• Language: English
• Subjects: Acetophenones - chemistry; Acetophenones - metabolism; Aspergillus; Aspergillus - isolation & purification; Aspergillus - metabolism; Biomedical and Life Sciences; Biotransformation; Disinfectants - chemistry; Disinfectants - metabolism; Engineering; enzymatic hydrolysis; Enzymes; ethylene oxide; Ethylene Oxide - chemistry; Ethylene Oxide - metabolism; Freshwater & Marine Ecology; Fungi; hydrolases; Hydrolysis; Life Sciences; Marine biology; marine fungi; Microbiology; Microorganisms; Original Article; Penicillium; Porifera; Propane; Spectrum analysis; Studies; Trichoderma; Trichoderma - isolation & purification; Trichoderma - metabolism; Water Microbiology; Water Pollutants, Chemical - chemistry; Water Pollutants, Chemical - metabolism; Zoology
• ISSN: 1436-2228; 1436-2236
• DOI: 10.1007/s10126-010-9302-2

Whole cells of the marine fungi Aspergillus sydowii Gc12, Penicillium raistrickii Ce16, P. miczynskii Gc5, and Trichoderma sp. Gc1, isolated from marine sponges of the South Atlantic Ocean (Brazil), have been screened for the enzymatic resolution of (±)-2-(benzyloxymethyl)oxirane (benzyl glycidyl ether; 1). Whole cells of A. sydowii Gc12 catalyzed the enzymatic hydrolysis of (R,S)-1 to yield (R)-1 with an enantiomeric excess (ee) of 24-46% and 3-(benzyloxy)propane-1,2-diol (2) with ee values