A Meta-Analysis of Neuropsychological Functioning in Patients with Early Onset Schizophrenia and Pediatric Bipolar Disorder

Despite the nosological distinction between bipolar disorder and schizophrenia, there is increasing evidence that these conditions share phenomenological characteristics. To examine the similarities in their patterns of cognitive impairment, we conducted a meta-analysis from 12 studies of Early Onse...

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Bibliographic Details
Published in:Journal of clinical child and adolescent psychology 2011-03, Vol.40 (2), p.266-280
Main Authors: Nieto, Rebeca García, Castellanos, F. Xavier
Format: Article
Language:English
Subjects:
Adolescence
Bipolar affective disorder
Bipolar disorder
Bipolar Disorder - psychology
Child psychology
Cognition & reasoning
Cognition - physiology
Cognitive ability
Cognitive Processes
Early onset
Executive function
Executive Function - physiology
Genetics
Humans
Learning
Memory
Memory - physiology
Mental Disorders
Meta Analysis
Neurological Impairments
Neuropsychological Tests
Neuropsychology
Paediatrics
Patients
Pediatrics
Phenomenology
Profiles
Psychosis
Reviews
Schizophrenia
Schizophrenic Psychology
Systematic review
Verbal Learning
Verbal memory
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Summary:Despite the nosological distinction between bipolar disorder and schizophrenia, there is increasing evidence that these conditions share phenomenological characteristics. To examine the similarities in their patterns of cognitive impairment, we conducted a meta-analysis from 12 studies of Early Onset Schizophrenia (EOS) and 12 studies of Pediatric Bipolar Disorder (PBD). We found that individuals with PBD suffer from cognitive deficits (e.g., verbal learning and memory, processing speed, or executive control) that are milder but similar in nature to those of patients with EOS. Qualitative similarities between the neuropsychological profiles produced by these groups of patients might represent a "continuum of psychosis" or reflect some degree of genetic biological overlap.
ISSN:1537-4416
1537-4424
DOI:10.1080/15374416.2011.546049