Prevalence and genotypic characteristics of [Beta]-lactamase-negative ampicillin-resistant Haemophilus influenzae in Australia

To determine the prevalence of β-lactamase-negative ampicillin-resistant (BLNAR) Haemophilus influenzae in Australia and characterize the associated amino acid substitutions in penicillin-binding protein 3. Two hundred consecutive non-repeat clinical isolates of H. influenzae were collected and β-la...

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Bibliographic Details
Published in:Journal of antimicrobial chemotherapy 2011-05, Vol.66 (5), p.1013
Main Authors: Witherden, Elizabeth A, Montgomery, Janet, Henderson, Barbara, Tristram, Stephen G
Format: Article
Language:English
Subjects:
Amino acids
Drug resistance
Genetics
Genotype & phenotype
Gram-negative bacteria
Penicillin
Proteins
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Summary:To determine the prevalence of β-lactamase-negative ampicillin-resistant (BLNAR) Haemophilus influenzae in Australia and characterize the associated amino acid substitutions in penicillin-binding protein 3. Two hundred consecutive non-repeat clinical isolates of H. influenzae were collected and β-lactamase-negative isolates were screened for reduced ampicillin susceptibility using an ampicillin 2 ...g disc (breakpoint
ISSN:0305-7453
1460-2091