Anthelmintic activity of the crude extracts of Ficus racemosa

The crude extracts of Ficus racemosa (Moraceae) were evaluated for anthelmintic activity using adult earthworms; the bark extract of Ficus racemosa exhibited a dose-dependent inhibition of spontaneous motility (paralysis) and evoked responses to pin-prick. With higher doses (50 mg/mL of aqueous extr...

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Bibliographic Details
Published in:International journal of green pharmacy 2008-04, Vol.2 (2), p.100
Main Authors: Latha, KP, Vagdevi, HM, Vaidya, VP, Chandrashekhar, CH
Format: Article
Language:English
Subjects:
Care and treatment
Ficus (Plants)
Health aspects
Helminthiasis
Herbal medicine
Parasitic diseases
Pharmacology
Properties
Risk factors
Trees
Worms
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Summary:The crude extracts of Ficus racemosa (Moraceae) were evaluated for anthelmintic activity using adult earthworms; the bark extract of Ficus racemosa exhibited a dose-dependent inhibition of spontaneous motility (paralysis) and evoked responses to pin-prick. With higher doses (50 mg/mL of aqueous extract), the effects were comparable with that of 3% piperazine citrate. However, there was no final recovery in the case of worms treated with aqueous extract in contrast to piperazine citrate with which the paralysis was reversible and the worms recovered completely within 5 h. The result shows that the aqueous extract possesses wormicidal activity and thus, may be useful as an anthelmintic.
ISSN:0973-8258
1998-4103
DOI:10.4103/0973-8258.41180