Silica-related rheumatoid arthritis without lung involvement

We report a young male with recent onset of rheumatoid arthritis (RA) in whom the remarkable severity of the disease led to additional investigations. The only significant finding was mediastinal lymphadenopathy, without lung involvement. Biopsy of the mediastinal lymph node revealed pathological fi...

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Bibliographic Details
Published in:Clinical rheumatology 2003-02, Vol.22 (1), p.53-55
Main Authors: Markovits, D, Schapira, D, Wiener, A, Nahir, A M
Format: Article
Language:English
Subjects:
Adult
Arthritis, Rheumatoid - etiology
Arthritis, Rheumatoid - physiopathology
Humans
Lung - pathology
Lymph Nodes - pathology
Lymphatic Diseases - etiology
Lymphatic Diseases - pathology
Male
Mediastinum
Medical research
Rheumatoid arthritis
Severity of Illness Index
Silicosis - complications
Silicosis - pathology
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Summary:We report a young male with recent onset of rheumatoid arthritis (RA) in whom the remarkable severity of the disease led to additional investigations. The only significant finding was mediastinal lymphadenopathy, without lung involvement. Biopsy of the mediastinal lymph node revealed pathological findings typical of silicosis. To our knowledge, this is the first report of silicosis apparent solely in the mediastinal lymph node of an RA patient. This suggests that lung involvement is not crucial for the development of silica-related arthritis.
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-002-0639-4