Renal diseases in ankylosing spondylitis: review of the literature illustrated by case reports

Ankylosing spondylitis (AS) can be accompanied by extraarticular manifestations in the cardiovascular, pulmonary, neurologic and renal organs. Secondary renal amyloidosis is the most common cause of renal involvement in AS (62%) followed by IgA nephropathy (30%), mesangioproliferative glomerulonephr...

Full description

Saved in:
Bibliographic Details
Published in:Clinical rheumatology 1998-01, Vol.17 (6), p.524-530
Main Authors: Strobel, E S, Fritschka, E
Format: Article
Language:English
Subjects:
Adolescent
Amyloidosis - etiology
Amyloidosis - pathology
Biopsy
Humans
Kidney diseases
Kidney Diseases - etiology
Kidney Diseases - pathology
Male
Middle Aged
Prevalence
Spondylitis, Ankylosing - complications
Spondylitis, Ankylosing - pathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Ankylosing spondylitis (AS) can be accompanied by extraarticular manifestations in the cardiovascular, pulmonary, neurologic and renal organs. Secondary renal amyloidosis is the most common cause of renal involvement in AS (62%) followed by IgA nephropathy (30%), mesangioproliferative glomerulonephritis (5%) as well as rarely membranous nephropathy (1%), focal segmental glomerulosclerosis (1%) and focal proliferative glomeruleonephritis (1%). Treatment associated nephrotoxicity may result from non-steroidal anti-inflammatory drugs or disease modifying agents. The purpose of this paper was to alert for the possibility of renal damage in AS and to analyse the frequencies of different etiologies of renal involvement. Two typical case reports of renal involvement in AS are presented to illustrate the clinical course of such patients. Renal side effects and possible pre-existing renal diseases should be taken into account while choosing the appropriate medication for patients with AS.
ISSN:0770-3198
1434-9949
DOI:10.1007/BF01451293