Reconfigurable Translocation of Microbeads Using Micro-Engineered Locally Controlled Magnetic Fields

A microfluidic platform for magnetic bead translocation is introduced, consisting of microfabricated magnetic devices. Each magnetic device was constructed of embedded actuation microcoil array in various designs, which enable efficient magnetic beads and magnetic bead-labeled cell translocation in...

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Bibliographic Details
Published in:Journal of microelectromechanical systems 2011-12, Vol.20 (6), p.1310-1323
Main Authors: Ramadan, Q., Lau Ting Ting
Format: Article
Language:English
Subjects:
Applied fluid mechanics
Arrays
Beads
Convergence
Current-carrying conductors
Exact sciences and technology
Fluid dynamics
Fluidics
Fundamental areas of phenomenology (including applications)
General equipment and techniques
Instruments, apparatus, components and techniques common to several branches of physics and astronomy
Magnetic devices
Magnetic fields
Magnetic forces
Magnetic separation
Magnetic switching
Magnetostatics
Mechanical instruments, equipment and techniques
micromagnetic beads
Micromechanical devices and systems
Microorganisms
Oscillations
Physics
Saturation magnetization
Soft magnetic materials
Transducers
translocation
Transportation
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Description
Summary:A microfluidic platform for magnetic bead translocation is introduced, consisting of microfabricated magnetic devices. Each magnetic device was constructed of embedded actuation microcoil array in various designs, which enable efficient magnetic beads and magnetic bead-labeled cell translocation in different patterns and step sizes. The translocation of magnetic beads and magnetic bead-labeled cells was demonstrated in three motion modes: transportation, oscillation, and convergence and divergence. The trapping and translocation efficiencies were measured and analyzed.
ISSN:1057-7157
1941-0158
DOI:10.1109/JMEMS.2011.2167675