Tris-2(hydroxyethyl)ammonium (2-methylphenoxy)acetate as an inhibitor of synthesis of acid cholesterol esterase of platelets and mononuclear cells

It is known that atherosclerosis is associated with pathological processes in the vascular endothelium. The purpose of this work was to study the effect of trecrezan on the total activity of AChE of platelets and monocytes in experimental atherosclerosis in rabbits.

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Bibliographic Details
Published in:Doklady. Biochemistry and biophysics 2011-12, Vol.441 (1), p.270-272
Main Authors: Rasulov, M. M., Bobkova, S. N., Belikova, O. A., Nurbekov, M. K., Shimanovskaya, N. P., Voronkov, M. G.
Format: Article
Language:English
Subjects:
Animals
Atherosclerosis
Atherosclerosis - drug therapy
Atherosclerosis - metabolism
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biophysics
Biophysics and Molecular Biology
Biosynthesis
Blood Coagulation - drug effects
Blood platelets
Blood Platelets - drug effects
Blood Platelets - enzymology
Cellular biology
Disease Models, Animal
Enzymes
Life Sciences
Lipid Metabolism - drug effects
Monocytes - drug effects
Monocytes - enzymology
Phenoxyacetates - pharmacology
Quaternary Ammonium Compounds - pharmacology
Rabbits
Sterol Esterase - drug effects
Sterol Esterase - metabolism
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Description
Summary:It is known that atherosclerosis is associated with pathological processes in the vascular endothelium. The purpose of this work was to study the effect of trecrezan on the total activity of AChE of platelets and monocytes in experimental atherosclerosis in rabbits.
ISSN:1607-6729
1608-3091
DOI:10.1134/S160767291106007X