Periodontitis and diabetes associations with measures of atherosclerosis and CHD

Highlights ► Severe periodontal disease and diabetes is associated with increased prevalence of IMT ≥ 1, acoustic shadowing, and CHD. ► Diabetes alone is associated with increased odds for IMT > 1 mm, but not shadowing or CHD. ► Periodontal disease increases the likelihood of subclinical atherosc...

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Bibliographic Details
Published in:Atherosclerosis 2012-05, Vol.222 (1), p.196-201
Main Authors: Southerland, Janet H, Moss, Kevin, Taylor, George W, Beck, James D, Pankow, James, Gangula, Pandu R, Offenbacher, Steven
Format: Article
Language:English
Subjects:
Acoustic shadowing
acoustics
Aged
Associated diseases and complications
atherosclerosis
Atherosclerosis (general aspects, experimental research)
Biological and medical sciences
Blood and lymphatic vessels
body mass index
calcification
Cardiology. Vascular system
Cardiovascular
carotid arteries
Carotid Intima-Media Thickness
Coronary Artery Disease - etiology
coronary disease
Coronary Disease - complications
Coronary Disease - etiology
Coronary heart disease
diabetes
Diabetes Complications
Diabetes Mellitus - pathology
Diabetes. Impaired glucose tolerance
education
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Female
gender
high density lipoprotein cholesterol
Humans
hypertension
income
Inflammatory mediators
Intimal–medial wall thickness
low density lipoprotein
Male
Medical sciences
Metabolic control
Middle Aged
multivariate analysis
people
Periodontal disease
periodontal diseases
Periodontitis - complications
Periodontitis - epidemiology
Periodontitis - pathology
regression analysis
Risk
triacylglycerols
United States - epidemiology
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Description
Summary:Highlights ► Severe periodontal disease and diabetes is associated with increased prevalence of IMT ≥ 1, acoustic shadowing, and CHD. ► Diabetes alone is associated with increased odds for IMT > 1 mm, but not shadowing or CHD. ► Periodontal disease increases the likelihood of subclinical atherosclerotic heart disease and CHD in diabetic patients. ► There is a need case definitions of periodontal disease that effectively capture systemic effects of sever forms of the disease. ► Further investigation is warranted to understand the interaction of diabetes and periodontal disease as it relates to increased prevalence of IMT, acoustic shadowing, and CHD.
ISSN:0021-9150
1879-1484
DOI:10.1016/j.atherosclerosis.2012.01.026