T-category reflects the histopathologic characteristics of gallbladder cancer

Abstract Aims Gallbladder (GB) cancer is a relatively uncommon gastrointestinal malignancy and is known to often result in unfavorable outcomes. Recent advances in aggressive surgical resection have improved the overall survival rate of patients with GB cancer. We aimed to evaluate the outcomes and...

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Bibliographic Details
Published in:European journal of surgical oncology 2012-06, Vol.38 (6), p.537-542
Main Authors: Cho, S.Y, Han, S.S, Park, S.J, Kim, Y.K, Kim, S.H, Woo, S.M, Lee, W.J, Kim, T.H, Hong, E.K
Format: Article
Language:English
Subjects:
Adult
Aged
Analysis of Variance
Biomarkers, Tumor - analysis
Chemotherapy, Adjuvant
Cholecystectomy - methods
Female
Gallbladder cancer
Gallbladder Neoplasms - diagnosis
Gallbladder Neoplasms - mortality
Gallbladder Neoplasms - pathology
Gallbladder Neoplasms - surgery
Hematology, Oncology and Palliative Medicine
Humans
Kaplan-Meier Estimate
Lymphatic Metastasis
Male
Middle Aged
Multivariate Analysis
Neoplasm Invasiveness
Neoplasm Staging
Neoplasm, Residual - diagnosis
Prognosis
Republic of Korea
Resection
Retrospective Studies
Risk Factors
Severity of Illness Index
Surgery
T-category
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Summary:Abstract Aims Gallbladder (GB) cancer is a relatively uncommon gastrointestinal malignancy and is known to often result in unfavorable outcomes. Recent advances in aggressive surgical resection have improved the overall survival rate of patients with GB cancer. We aimed to evaluate the outcomes and prognostic factors of GB cancer following a surgical resection with curative intent. Methods Between March 2001 and March 2009, 89 patients with GB cancer underwent surgical resection with curative intent at the National Cancer Center of Korea. We then conducted a retrospective analysis of clinicopathologic data. Results Nineteen patients underwent simple cholecystectomy and 70 patients underwent extended cholecystectomy. Tumor-free resection margins were obtained in 84 cases. The 1-, 3- and 5-year disease-specific survival rates in the 89 patients were 85.8%, 68.0% and 64.1%, respectively. By multivariate analysis, only the T-category was significant ( p  
ISSN:0748-7983
1532-2157
DOI:10.1016/j.ejso.2012.01.009