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High-Frequency Oscillatory Ventilation for Rescue From Refractory Hypoxemia in a Patient With Transfusion-Related Acute Lung Injury

Transfusion-related acute lung injury is a serious complication of blood transfusions. Herein is a report on a 32-year-old woman who developed diffuse pulmonary infiltrates and acute respiratory compromise after blood transfusion. Non-cardiogenic pulmonary edema was diagnosed based on data calculate...

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Bibliographic Details
Published in:Respiratory care 2012-05, Vol.57 (5), p.798-801
Main Authors: HUANG, Chin-Hua, HU, Han-Chung, HSIEH, Meng-Jer, HUANG, Ching-Tzu, CHO, Hsiu-Ying, HSIAO, Hsiu-Feng, YANG, Cheng-Ta, TSAI, Ying-Huang, HUANG, Chung-Chi, KAO, Kuo-Chin
Format: Article
Language:English
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Summary:Transfusion-related acute lung injury is a serious complication of blood transfusions. Herein is a report on a 32-year-old woman who developed diffuse pulmonary infiltrates and acute respiratory compromise after blood transfusion. Non-cardiogenic pulmonary edema was diagnosed based on data calculated by the hemodynamic monitoring system, but severe hypoxemia persisted despite conventional pressure-control ventilation with 100% oxygen, low tidal volume, and high PEEP. The refractory hypoxemia was improved by high-frequency oscillatory ventilation. This experience suggests that high-frequency oscillatory ventilation may be beneficial for patients with transfusion-related acute lung injury and severe refractory hypoxemia.
ISSN:0020-1324
1943-3654
DOI:10.4187/respcare.01355