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Pregnancy outcome after third trimester amniocentesis: a single center experience
Objective: To evaluate pregnancy outcome following late amniocentesis (>24 weeks of gestation). Study design: A retrospective cohort of all women with singleton pregnancy that underwent late amniocentesis in one tertiary center. Results: Pregnancy outcome was validated in 168 women who underwent...
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Published in: | The journal of maternal-fetal & neonatal medicine 2012-06, Vol.25 (6), p.666-668 |
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container_title | The journal of maternal-fetal & neonatal medicine |
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creator | Gabbay, Rinat Yogev, Yariv Melamed, Nir Ben-Haroush, Avi Meizner, Israel Pardo, Joseph |
description | Objective: To evaluate pregnancy outcome following late amniocentesis (>24 weeks of gestation). Study design: A retrospective cohort of all women with singleton pregnancy that underwent late amniocentesis in one tertiary center. Results: Pregnancy outcome was validated in 168 women who underwent late amniocentesis. Overall, for the all study group the mean gestational age for amniocentesis was 31.6 ± 2.3 weeks and the mean gestational age at delivery was 38.1 ± 2. Indications for late amniocentesis included abnormal ultrasonographic findings (n = 120), suspected intrauterine infection (n = 23), advanced maternal age (n = 13), abnormal first or second trimester biochemical markers (n = 8) and others. The overall rate of spontaneous preterm delivery ( |
doi_str_mv | 10.3109/14767058.2011.594119 |
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Study design: A retrospective cohort of all women with singleton pregnancy that underwent late amniocentesis in one tertiary center. Results: Pregnancy outcome was validated in 168 women who underwent late amniocentesis. Overall, for the all study group the mean gestational age for amniocentesis was 31.6 ± 2.3 weeks and the mean gestational age at delivery was 38.1 ± 2. Indications for late amniocentesis included abnormal ultrasonographic findings (n = 120), suspected intrauterine infection (n = 23), advanced maternal age (n = 13), abnormal first or second trimester biochemical markers (n = 8) and others. The overall rate of spontaneous preterm delivery (<37 weeks) was 8% (13/168) with mean gestational age at delivery of 34.7 ± 1.3. In only five cases (3%), delivery occurred ≤ 34 weeks of gestation. In one case (0.60%) of amniocentesis performed at 32 weeks of gestation, delivery occurred within 48 hours and in other four cases (2.40%) delivery occurred within 10 days. When amniocentesis was performed due to ultrasonographic findings to rule out chromosomal abnormalities (n = 117/182), abnormal karyotype was found only in three cases. Conclusions: The risk of significant prematurity following late amniocentesis is low. This information is important when counseling patients considering performing one.</description><identifier>ISSN: 1476-7058</identifier><identifier>EISSN: 1476-4954</identifier><identifier>DOI: 10.3109/14767058.2011.594119</identifier><identifier>PMID: 21834751</identifier><language>eng</language><publisher>England: Informa Healthcare</publisher><subject>Adult ; Amniocentesis - adverse effects ; Amniocentesis - statistics & numerical data ; Amniocentesis - utilization ; Cohort Studies ; Delivery, Obstetric - methods ; Delivery, Obstetric - statistics & numerical data ; Female ; Follow-Up Studies ; genetic ; Gestational Age ; Humans ; late amniocentesis ; Obstetric Labor, Premature - epidemiology ; Obstetric Labor, Premature - etiology ; Predictive Value of Tests ; Pregnancy ; Pregnancy Complications - epidemiology ; Pregnancy Complications - etiology ; pregnancy outcome ; Pregnancy Outcome - epidemiology ; Pregnancy Trimester, Third ; preterm labor ; Retrospective Studies ; Validation Studies as Topic ; Young Adult</subject><ispartof>The journal of maternal-fetal & neonatal medicine, 2012-06, Vol.25 (6), p.666-668</ispartof><rights>2012 Informa UK, Ltd. 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c418t-ea8f3c21c1f2e26b107bd56b72af24b16df649976896caf159c8ebdeff2213033</citedby><cites>FETCH-LOGICAL-c418t-ea8f3c21c1f2e26b107bd56b72af24b16df649976896caf159c8ebdeff2213033</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21834751$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gabbay, Rinat</creatorcontrib><creatorcontrib>Yogev, Yariv</creatorcontrib><creatorcontrib>Melamed, Nir</creatorcontrib><creatorcontrib>Ben-Haroush, Avi</creatorcontrib><creatorcontrib>Meizner, Israel</creatorcontrib><creatorcontrib>Pardo, Joseph</creatorcontrib><title>Pregnancy outcome after third trimester amniocentesis: a single center experience</title><title>The journal of maternal-fetal & neonatal medicine</title><addtitle>J Matern Fetal Neonatal Med</addtitle><description>Objective: To evaluate pregnancy outcome following late amniocentesis (>24 weeks of gestation). Study design: A retrospective cohort of all women with singleton pregnancy that underwent late amniocentesis in one tertiary center. Results: Pregnancy outcome was validated in 168 women who underwent late amniocentesis. Overall, for the all study group the mean gestational age for amniocentesis was 31.6 ± 2.3 weeks and the mean gestational age at delivery was 38.1 ± 2. Indications for late amniocentesis included abnormal ultrasonographic findings (n = 120), suspected intrauterine infection (n = 23), advanced maternal age (n = 13), abnormal first or second trimester biochemical markers (n = 8) and others. The overall rate of spontaneous preterm delivery (<37 weeks) was 8% (13/168) with mean gestational age at delivery of 34.7 ± 1.3. In only five cases (3%), delivery occurred ≤ 34 weeks of gestation. In one case (0.60%) of amniocentesis performed at 32 weeks of gestation, delivery occurred within 48 hours and in other four cases (2.40%) delivery occurred within 10 days. When amniocentesis was performed due to ultrasonographic findings to rule out chromosomal abnormalities (n = 117/182), abnormal karyotype was found only in three cases. Conclusions: The risk of significant prematurity following late amniocentesis is low. This information is important when counseling patients considering performing one.</description><subject>Adult</subject><subject>Amniocentesis - adverse effects</subject><subject>Amniocentesis - statistics & numerical data</subject><subject>Amniocentesis - utilization</subject><subject>Cohort Studies</subject><subject>Delivery, Obstetric - methods</subject><subject>Delivery, Obstetric - statistics & numerical data</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>genetic</subject><subject>Gestational Age</subject><subject>Humans</subject><subject>late amniocentesis</subject><subject>Obstetric Labor, Premature - epidemiology</subject><subject>Obstetric Labor, Premature - etiology</subject><subject>Predictive Value of Tests</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - epidemiology</subject><subject>Pregnancy Complications - etiology</subject><subject>pregnancy outcome</subject><subject>Pregnancy Outcome - epidemiology</subject><subject>Pregnancy Trimester, Third</subject><subject>preterm labor</subject><subject>Retrospective Studies</subject><subject>Validation Studies as Topic</subject><subject>Young Adult</subject><issn>1476-7058</issn><issn>1476-4954</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp9kE1rGzEQhkVoiBO3_yCEPfZiR6PVfqiHlmLyBYGk0J6FVjuKFXYlV9ql8b-PtnYCufgkaXjmndFDyDnQZQ5UXAKvyooW9ZJRgGUhOIA4IqdTecFFwT_t7xMzI2cxPlPKgNPihMwY1DmvCjglvx4DPjnl9Dbz46B9j5kyA4ZsWNvQZkOwPcbprXpnvUY3YLTxW6ayaN1Th9n_UsjwZYPBotP4mRwb1UX8sj_n5M_11e_V7eL-4eZu9fN-oTnUwwJVbXLNQINhyMoGaNW0RdlUTBnGGyhbU3IhqrIWpVYGCqFrbFo0hjHIaZ7Pyddd7ib4v2NaUvY2auw65dCPUQKFPBkSokwo36E6-BgDGrlJ_1JhmyA5yZRvMuUkU-5kpraL_YSx6bF9b3qzl4AfO8A640Ov_vnQtXJQ284HE5JUG6f4gyO-f0hYo-qGtVYB5bMfg0sCD-_4CsQpl9o</recordid><startdate>201206</startdate><enddate>201206</enddate><creator>Gabbay, Rinat</creator><creator>Yogev, Yariv</creator><creator>Melamed, Nir</creator><creator>Ben-Haroush, Avi</creator><creator>Meizner, Israel</creator><creator>Pardo, Joseph</creator><general>Informa Healthcare</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201206</creationdate><title>Pregnancy outcome after third trimester amniocentesis: a single center experience</title><author>Gabbay, Rinat ; Yogev, Yariv ; Melamed, Nir ; Ben-Haroush, Avi ; Meizner, Israel ; Pardo, Joseph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c418t-ea8f3c21c1f2e26b107bd56b72af24b16df649976896caf159c8ebdeff2213033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Amniocentesis - adverse effects</topic><topic>Amniocentesis - statistics & numerical data</topic><topic>Amniocentesis - utilization</topic><topic>Cohort Studies</topic><topic>Delivery, Obstetric - methods</topic><topic>Delivery, Obstetric - statistics & numerical data</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>genetic</topic><topic>Gestational Age</topic><topic>Humans</topic><topic>late amniocentesis</topic><topic>Obstetric Labor, Premature - epidemiology</topic><topic>Obstetric Labor, Premature - etiology</topic><topic>Predictive Value of Tests</topic><topic>Pregnancy</topic><topic>Pregnancy Complications - epidemiology</topic><topic>Pregnancy Complications - etiology</topic><topic>pregnancy outcome</topic><topic>Pregnancy Outcome - epidemiology</topic><topic>Pregnancy Trimester, Third</topic><topic>preterm labor</topic><topic>Retrospective Studies</topic><topic>Validation Studies as Topic</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gabbay, Rinat</creatorcontrib><creatorcontrib>Yogev, Yariv</creatorcontrib><creatorcontrib>Melamed, Nir</creatorcontrib><creatorcontrib>Ben-Haroush, Avi</creatorcontrib><creatorcontrib>Meizner, Israel</creatorcontrib><creatorcontrib>Pardo, Joseph</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The journal of maternal-fetal & neonatal medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gabbay, Rinat</au><au>Yogev, Yariv</au><au>Melamed, Nir</au><au>Ben-Haroush, Avi</au><au>Meizner, Israel</au><au>Pardo, Joseph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pregnancy outcome after third trimester amniocentesis: a single center experience</atitle><jtitle>The journal of maternal-fetal & neonatal medicine</jtitle><addtitle>J Matern Fetal Neonatal Med</addtitle><date>2012-06</date><risdate>2012</risdate><volume>25</volume><issue>6</issue><spage>666</spage><epage>668</epage><pages>666-668</pages><issn>1476-7058</issn><eissn>1476-4954</eissn><abstract>Objective: To evaluate pregnancy outcome following late amniocentesis (>24 weeks of gestation). Study design: A retrospective cohort of all women with singleton pregnancy that underwent late amniocentesis in one tertiary center. Results: Pregnancy outcome was validated in 168 women who underwent late amniocentesis. Overall, for the all study group the mean gestational age for amniocentesis was 31.6 ± 2.3 weeks and the mean gestational age at delivery was 38.1 ± 2. Indications for late amniocentesis included abnormal ultrasonographic findings (n = 120), suspected intrauterine infection (n = 23), advanced maternal age (n = 13), abnormal first or second trimester biochemical markers (n = 8) and others. The overall rate of spontaneous preterm delivery (<37 weeks) was 8% (13/168) with mean gestational age at delivery of 34.7 ± 1.3. In only five cases (3%), delivery occurred ≤ 34 weeks of gestation. In one case (0.60%) of amniocentesis performed at 32 weeks of gestation, delivery occurred within 48 hours and in other four cases (2.40%) delivery occurred within 10 days. When amniocentesis was performed due to ultrasonographic findings to rule out chromosomal abnormalities (n = 117/182), abnormal karyotype was found only in three cases. Conclusions: The risk of significant prematurity following late amniocentesis is low. This information is important when counseling patients considering performing one.</abstract><cop>England</cop><pub>Informa Healthcare</pub><pmid>21834751</pmid><doi>10.3109/14767058.2011.594119</doi><tpages>3</tpages></addata></record> |
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subjects | Adult Amniocentesis - adverse effects Amniocentesis - statistics & numerical data Amniocentesis - utilization Cohort Studies Delivery, Obstetric - methods Delivery, Obstetric - statistics & numerical data Female Follow-Up Studies genetic Gestational Age Humans late amniocentesis Obstetric Labor, Premature - epidemiology Obstetric Labor, Premature - etiology Predictive Value of Tests Pregnancy Pregnancy Complications - epidemiology Pregnancy Complications - etiology pregnancy outcome Pregnancy Outcome - epidemiology Pregnancy Trimester, Third preterm labor Retrospective Studies Validation Studies as Topic Young Adult |
title | Pregnancy outcome after third trimester amniocentesis: a single center experience |
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