Facial and axillary apocrine chromhidrosis

Apocrine chromhidrosis is a rare, chronic, idiopathic disorder, characterized by the excretion of pigmented sweat. A 26-year-old woman presented with a 3-year history of dark blue secretions on bilateral malar cheeks. On examination, upon pressure on the cheeks, a dark blue fluid was expressed, whic...

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Bibliographic Details
Published in:Dermatology online journal 2012-03, Vol.18 (3), p.13-13
Main Authors: Pérez Tato, Berta, Zamora Martínez, Elena, Sánchez Albisua, Begoña, Pérez González, Yosmar C, Polimón Olabarrieta, Isabel, Marinero Escobedo, Silvia, Fernández López, Paloma
Format: Article
Language:English
Subjects:
Adult
Aluminum Compounds - therapeutic use
Apocrine Glands - pathology
Botulinum Toxins, Type A - therapeutic use
Capsaicin - therapeutic use
Cheek - pathology
Chlorides - therapeutic use
Dermatologic Agents - therapeutic use
Female
Humans
Lipofuscin - analysis
Pigmentation Disorders - diagnosis
Pigmentation Disorders - drug therapy
Pigmentation Disorders - pathology
Sweat - drug effects
Sweat Gland Diseases - diagnosis
Sweat Gland Diseases - drug therapy
Sweat Gland Diseases - pathology
Treatment Outcome
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Summary:Apocrine chromhidrosis is a rare, chronic, idiopathic disorder, characterized by the excretion of pigmented sweat. A 26-year-old woman presented with a 3-year history of dark blue secretions on bilateral malar cheeks. On examination, upon pressure on the cheeks, a dark blue fluid was expressed, which appeared to arise primarily from the follicle. The patient had not appreciated it, but on examination of her axillae, a very subtle blue coloring was observed. Histopathologic examination revealed apocrine glands in the deep reticular dermis. Bluish cytoplasmic granules were observed in the apocrine epithelium lining, which correspond to lipofuscin granules. The diagnosis of apocrine cromhidrosis was made. We began treatment with 20 percent aluminum chloride hexahydrate solution and capsaicin cream with poor tolerance. Finally, we treated with botulinum toxin type A with a successful response. We report a case of facial and axillary apocrine cromhidrosis with good response to botulinum toxin type A.
ISSN:1087-2108
1087-2108
DOI:10.5070/D34md22376