Seizure During Hyperbaric Oxygen Therapy for Carbon Monoxide Toxicity: A Case Series and Five-year Experience

Abstract Background: Hyperbaric oxygen (HBO) therapy is recommended to reduce the delayed neurologic sequelae resulting from carbon monoxide (CO) toxicity. Although HBO is generally well tolerated, there exists a risk of seizure in all patients that may be increased in patients with predisposing fac...

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Bibliographic Details
Published in:The Journal of emergency medicine 2012-04, Vol.42 (4), p.e69-e72
Main Authors: Sanders, Robert W., MD, DMT, Katz, Kenneth D., MD, Suyama, Joe, MD, Akhtar, Jawaid, MD, O'Toole, Kevin S., MD, Corll, Diann, RN, Ladenburger, Regan N., MD
Format: Article
Language:English
Subjects:
Aged
carbon monoxide
Carbon Monoxide Poisoning - therapy
Emergency
Female
Humans
hyperbaric oxygen
Hyperbaric Oxygenation - adverse effects
Male
Middle Aged
oxygen toxicity
poisoning
Risk Factors
seizure
Seizures - epidemiology
Seizures - etiology
structure fire
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Summary:Abstract Background: Hyperbaric oxygen (HBO) therapy is recommended to reduce the delayed neurologic sequelae resulting from carbon monoxide (CO) toxicity. Although HBO is generally well tolerated, there exists a risk of seizure in all patients that may be increased in patients with predisposing factors including: fever, hypothermia, prior seizure, or brain injury. Case Report: We present two cases of patients without known risk factors who experienced seizures associated with HBO therapy during treatment for CO toxicity. Conclusion: This facility's 5-year experience and a review of the germane literature are also presented to elucidate the risk factors and incidence of seizures in patients treated with HBO for CO toxicity.
ISSN:0736-4679
2352-5029
DOI:10.1016/j.jemermed.2008.12.017