Resection Margin with Anatomic or Nonanatomic Hepatectomy for Liver Metastasis from Colorectal Cancer

Background When hepatectomy is used as a primary treatment for liver metastasis from colorectal cancer (CRCLM), the balance between surgical curability and functional preservation of the remnant liver is of great importance. Methods A total of 108 patients who underwent initial hepatectomy for CRCLM...

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Bibliographic Details
Published in:Journal of gastrointestinal surgery 2012-06, Vol.16 (6), p.1171-1180
Main Authors: Inoue, Yoshihiro, Hayashi, Michihiro, Komeda, Koji, Masubuchi, Shinsuke, Yamamoto, Masashi, Yamana, Hidenori, Kayano, Hajime, Shimizu, Tetsunosuke, Asakuma, Mitsuhiro, Hirokawa, Fumitoshi, Miyamoto, Yoshiharu, Takeshita, Atsushi, Shibayama, Yuro, Uchiyama, Kazuhisa
Format: Article
Language:English
Subjects:
Antigens
Colorectal cancer
Colorectal Neoplasms - mortality
Colorectal Neoplasms - pathology
Colorectal Neoplasms - surgery
Follow-Up Studies
Gastroenterology
Hepatectomy
Hepatectomy - methods
Hepatitis
Hospitals
Humans
Incidence
Japan - epidemiology
Liver cancer
Liver Neoplasms - mortality
Liver Neoplasms - secondary
Liver Neoplasms - surgery
Medical prognosis
Medicine
Medicine & Public Health
Metastasis
Neoplasm Recurrence, Local - epidemiology
Original Article
Patients
Prognosis
Retrospective Studies
Surgery
Survival Rate - trends
Tumors
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Summary:Background When hepatectomy is used as a primary treatment for liver metastasis from colorectal cancer (CRCLM), the balance between surgical curability and functional preservation of the remnant liver is of great importance. Methods A total of 108 patients who underwent initial hepatectomy for CRCLM were retrospectively analyzed with respect to tumor extent, operative method, and prognosis, including recurrence. Results The 1-, 2-, 3-, and 5-year overall survival rates (OS) for all patients were 90.5%, 77.8%, 63.2%, and 51.6%, respectively. Multivariate analysis indicated serum carbohydrate antigen 19-9 (CA 19-9) level after hepatectomy (
ISSN:1091-255X
1873-4626
DOI:10.1007/s11605-012-1840-7