Meta analysis of the curative effect of acupuncture on post-stroke depression

• Published in: Journal of traditional Chinese medicine 2012-03, Vol.32 (1), p.6-11
• Main Author: 张光彩 符文彬 许能贵 刘健华 朱晓平 梁兆辉 黄叶飞 陈远芳
• Format: Article
• Language: English
• Subjects: Acupuncture Therapy; Antidepressive Agents - therapeutic use; Depression - drug therapy; Depression - etiology; Depression - therapy; Humans; Meta分析; Randomized Controlled Trials as Topic; Stroke - complications; 中风; 信息资源系统; 抑郁症; 数据库检索; 疗效; 针灸治疗; 随机对照试验
• ISSN: 0255-2922
• DOI: 10.1016/S0254-6272(12)60024-7

OBJECTIVE：To systematically evaluate the curative effect of acupuncture on post-stroke depression（PSD）.METHODS：The internet was used to retrieve the Wanfang Medical Data System,Chinese Periodical Net,the Weipu Information Resources System,PubMed and the Cochrane Library Database.Relevant articles,up to September 2010,were manually retrieved.These papers included studies that had performed random and semi-random control trials for the use of acupuncture to treat PSD.Fifteen random control tests involving 1096 patients were included in this study and individual cases,interventional measures and curative effects were extracted from this research.Grade methodological quality evaluation and meta-analysis were performed on these studies.RESULTS：Comparison between the acupuncture group and the Western medicine group for the curative rate on PSD revealed an OR of 1.48,95% CI = [1.11 1.97] and P=0.008.Comparison of obviously effective rate shows that OR=1.39,95% CI=[1.08 1.80] and P=0.01.Comparison of effective rate showsthatOR=0.83,95%CI=[0.631.09]andP=0.18.CONCLUSION：Comparison between the acupuncture group and Western medicine group in treating PSD revealed that there is a statistical difference in curative rate and remarkably effective rate,but no difference in effective rate.