Association between traditional cholesterol parameters, lipoprotein particle concentration, novel biomarkers and carotid plaques in retired National Football League players

Highlights ► We assessed the association between lipid parameters and carotid plaques in retired NFL players. ► Carotid artery plaques were common and seen in 41% of retired NFL players. ► Plaques were more strongly associated with LDL particle concentration than LDL cholesterol.

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Bibliographic Details
Published in:Atherosclerosis 2012-06, Vol.222 (2), p.551-556
Main Authors: Virani, Salim S, Pompeii, Lisa, Lincoln, Andrew E, Dunn, Reginald E, Tucker, Andrew M, Nambi, Vijay, Nasir, Khurram, Vogel, Robert A, Boone, Jeffrey L, Roberts, Arthur J, Ballantyne, Christie M
Format: Article
Language:English
Subjects:
Adult
Aged
Asymptomatic Diseases
atherosclerosis
Atherosclerosis (general aspects, experimental research)
Biological and medical sciences
Biomarkers
Biomarkers - blood
Blood and lymphatic vessels
C-reactive protein
C-Reactive Protein - analysis
Cardiology. Vascular system
Cardiovascular
carotid arteries
Carotid Arteries - diagnostic imaging
Carotid Arteries - pathology
Carotid Artery Diseases - blood
Carotid Artery Diseases - diagnosis
Carotid Artery Diseases - diagnostic imaging
Carotid Artery Diseases - epidemiology
Carotid Artery Diseases - pathology
Cholesterol
Cholesterol - blood
Cholesterol, LDL - blood
confidence interval
Cross-Sectional Studies
Football
Fundamental and applied biological sciences. Psychology
General aspects
Humans
Lipoproteins
Lipoproteins, LDL - blood
Logistic Models
low density lipoprotein
Male
Medical sciences
metabolic syndrome
Metabolic Syndrome - blood
Metabolic Syndrome - epidemiology
Middle Aged
Odds Ratio
Plaque, Atherosclerotic
Predictive Value of Tests
Prevalence
regression analysis
Retired NFL players
Retirement
Risk Assessment
Risk Factors
screening
Subclinical atherosclerosis
Ultrasonography, Doppler
United States - epidemiology
Vertebrates: cardiovascular system
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Description
Summary:Highlights ► We assessed the association between lipid parameters and carotid plaques in retired NFL players. ► Carotid artery plaques were common and seen in 41% of retired NFL players. ► Plaques were more strongly associated with LDL particle concentration than LDL cholesterol.
ISSN:0021-9150
1879-1484
DOI:10.1016/j.atherosclerosis.2012.03.031