Scedosporium apiospermum atrial mycetomas after lung transplantation for cystic fibrosis

: A 37‐year‐old patient with cystic fibrosis underwent double lung transplantation. She developed disseminated Scedosporium apiospermum infection 2 months after surgery. Along with multiple brain abscesses, lung infection, and chorioretinitis, a cardiac echo revealed 2 large intra‐atrial mycetomas f...

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Bibliographic Details
Published in:Transplant infectious disease 2012-04, Vol.14 (2), p.188-191
Main Authors: Miraldi, F., Anile, M., Ruberto, F., Tritapepe, L., Puglese, F., Quattrucci, S., Messina, T., Vitolo, D., Venuta, F.
Format: Article
Language:English
Subjects:
Abscesses
Adult
Antifungal Agents - administration & dosage
Antifungal Agents - therapeutic use
atrial mycetoma
Brain
Chorioretinitis
Cystic fibrosis
Cystic Fibrosis - therapy
Fatal Outcome
Female
fungal infection
Heart
Heart Atria - pathology
Hemorrhage
Humans
Infection
Lung transplantation
Lung Transplantation - adverse effects
Mycetoma - microbiology
Mycetoma - pathology
Scedosporium - isolation & purification
Scedosporium apiospermum
Surgery
Veins
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Description
Summary:: A 37‐year‐old patient with cystic fibrosis underwent double lung transplantation. She developed disseminated Scedosporium apiospermum infection 2 months after surgery. Along with multiple brain abscesses, lung infection, and chorioretinitis, a cardiac echo revealed 2 large intra‐atrial mycetomas floating close to the right upper pulmonary vein orifice. The mycetomas were removed through a trans‐atrial approach under cardiopulmonary by pass; histology and cultures confirmed the diagnosis. Despite intensive treatment, the patient succumbed from massive brain hemorrhage on the 10th postoperative day.
ISSN:1398-2273
1399-3062
DOI:10.1111/j.1399-3062.2011.00679.x