Functional markers in wheat: current status and future prospects

Functional markers (FM) are developed from sequence polymorphisms present in allelic variants of a functional gene at a locus. FMs accurately discriminate alleles of a targeted gene, and are ideal molecular markers for marker-assisted selection in wheat breeding. In this paper, we summarize FMs deve...

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Bibliographic Details
Published in:Theoretical and applied genetics 2012-06, Vol.125 (1), p.1-10
Main Authors: Liu, Yanan, He, Zhonghu, Appels, Rudi, Xia, Xianchun
Format: Article
Language:English
Subjects:
Agriculture
Biochemistry
Biomedical and Life Sciences
Biotechnology
Breeding
Chromosomes
Cloning
Corn
Cultivars
Genes
Genes, Plant - genetics
Genetic aspects
Genetic Markers
Genetic polymorphisms
Genomes
Genomics
Life Sciences
Physiological aspects
Plant Biochemistry
Plant Breeding/Biotechnology
Plant Genetics and Genomics
Quantitative Trait, Heritable
Review
Species Specificity
Triticum - genetics
Triticum aestivum
Wheat
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Summary:Functional markers (FM) are developed from sequence polymorphisms present in allelic variants of a functional gene at a locus. FMs accurately discriminate alleles of a targeted gene, and are ideal molecular markers for marker-assisted selection in wheat breeding. In this paper, we summarize FMs developed and used in common wheat. To date, more than 30 wheat loci associated with processing quality, agronomic traits, and disease resistance, have been cloned, and 97 FMs were developed to identify 93 alleles based on the sequences of those genes. A general approach is described for isolation of wheat genes and development of FMs based on in silico cloning and comparative genomics. The divergence of DNA sequences of different alleles that affect gene function is summarized. In addition, 14 molecular markers specific for alien genes introduced from common wheat relatives were also described. This paper provides updated information on all FMs and gene-specific STS markers developed so far in wheat and should facilitate their application in wheat breeding programs.
ISSN:0040-5752
1432-2242
DOI:10.1007/s00122-012-1829-3