Status dystonicus: Predictors of outcome and progression patterns of underlying disease

Background: Status dystonicus (SD) is a rare, life‐threatening disorder characterized by acute worsening of generalized dystonia. Methods: This study was conducted to characterize the pathogenesis, clinical course, and prognosis of SD. We reviewed the records of six centers and analyzed them togethe...

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Bibliographic Details
Published in:Movement disorders 2012-05, Vol.27 (6), p.783-788
Main Authors: Fasano, Alfonso, Ricciardi, Lucia, Bentivoglio, Anna Rita, Canavese, Carlotta, Zorzi, Giovanna, Petrovic, Igor, Kresojevic, Nikola, Kostić, Vladimir S., Svetel, Marina, Kovacs, Norbert, Balas, Istvan, Roubertie, Agathe, Mishra, Devendra, Mariotti, Paolo, Temudo, Teresa, Nardocci, Nardo
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Biological and medical sciences
Child
Child, Preschool
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Disease Progression
dystonia
Dystonic Disorders - diagnosis
Dystonic Disorders - drug therapy
Dystonic Disorders - etiology
dystonic storm
Female
Humans
Male
Medical sciences
midazolam
Muscle Relaxants, Central - therapeutic use
Neurology
pantothenate-kinase-associated neurodegeneration
Prognosis
Sex Factors
status dystonicus
Treatment Outcome
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Summary:Background: Status dystonicus (SD) is a rare, life‐threatening disorder characterized by acute worsening of generalized dystonia. Methods: This study was conducted to characterize the pathogenesis, clinical course, and prognosis of SD. We reviewed the records of six centers and analyzed them together with all the cases previously reported in the literature. Results: Eighty‐nine episodes occurring in 68 patients were studied. The majority of patients were males (64.7%), were
ISSN:0885-3185
1531-8257
DOI:10.1002/mds.24981