Xanthogranulomatous Pyelonephritis—Mimicking Renal Mass in 5-Month-old Child

Xanthogranulomatous pyelonephritis is a rare, chronic inflammatory lesion of the kidney associated with chronic infection and obstruction. It is uncommon in children and extremely rare in infants. Because of its rarity, the condition is often not considered in the differential diagnosis of a renal m...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2012-06, Vol.79 (6), p.1360-1362
Main Authors: Shah, Kamlesh, Parikh, Mitul, Gharia, Parimalsinh, Modi, Pranjal R
Format: Article
Language:English
Subjects:
Biological and medical sciences
Diagnosis, Differential
Humans
Infant
Interstitial nephritis
Kidney - diagnostic imaging
Kidney Neoplasms - diagnosis
Male
Medical sciences
Nephrectomy
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Pyelonephritis, Xanthogranulomatous - diagnosis
Pyelonephritis, Xanthogranulomatous - surgery
Tomography, X-Ray Computed
Urology
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Summary:Xanthogranulomatous pyelonephritis is a rare, chronic inflammatory lesion of the kidney associated with chronic infection and obstruction. It is uncommon in children and extremely rare in infants. Because of its rarity, the condition is often not considered in the differential diagnosis of a renal mass in children. We report a case of a 5-month-old boy presenting with fever and a left renal mass. The findings from radiologic investigations were suggestive of a renal mass and urine culture suggestive of urinary tract infection. Left radical nephrectomy was performed with difficulty because of the dense adhesions to the adjacent structures. Histopathologic examination confirmed the diagnosis of xanthogranulomatous pyelonephritis.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2011.11.044