Predicting stroke evolution: comparison of susceptibility-weighted MR imaging with MR perfusion

Objectives To investigate the ability of susceptibility-weighted imaging (SWI) to predict stroke evolution in comparison with perfusion-weighted imaging (PWI). Methods In a retrospective analysis of 15 patients with non-lacunar ischaemic stroke studied no later than 24 h after symptom onset, we used...

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Bibliographic Details
Published in:European radiology 2012-07, Vol.22 (7), p.1397-1403
Main Authors: Kao, Hung-Wen, Tsai, Fong Y., Hasso, Anton N.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Blood
Brain Ischemia - complications
Brain Ischemia - pathology
Contrast agents
Diagnostic Radiology
Diffusion Magnetic Resonance Imaging - methods
Female
Humans
Imaging
Internal Medicine
Interventional Radiology
Ischemia
Magnetic Resonance Angiography - methods
Magnetic resonance imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Neuro
Neuroradiology
Radiology
Reproducibility of Results
Sensitivity and Specificity
Stroke
Stroke - complications
Stroke - pathology
Ultrasound
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Summary:Objectives To investigate the ability of susceptibility-weighted imaging (SWI) to predict stroke evolution in comparison with perfusion-weighted imaging (PWI). Methods In a retrospective analysis of 15 patients with non-lacunar ischaemic stroke studied no later than 24 h after symptom onset, we used the Alberta Stroke Program Early CT Score (ASPECTS) to compare lesions on initial diffusion-weighted images (DWI), SWI, PWI and follow-up studies obtained at least 5 days after symptom onset. The National Institutes of Health Stroke Scale scores at entry and stroke risk factors were documented. The clinical–DWI, SWI–DWI and PWI–DWI mismatches were calculated. Results SWI–DWI and mean transit time (MTT)–DWI mismatches were significantly associated with higher incidence of infarct growth ( P  = 0.007 and 0.028) and had similar ability to predict stroke evolution ( P  = 1.0). ASPECTS values on initial DWI, SWI and PWI were significantly correlated with those on follow-up studies ( P  ≤ 0.026) but not associated with infarct growth. The SWI ASPECTS values were best correlated with MTT ones ( ρ  = 0.8, P  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-012-2387-4