Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids

A study investigated the occurrence, biogenesis and synthesis of biologically active carbazole alkaloids, which can be constructed by cycling biphenyls with an orthonitrogen substitute or diarylamines. Fischer-Borche synthesis is one avenue by which carbazoles can be prepared.

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Bibliographic Details
Published in:Chemical reviews 2012-06, Vol.112 (6), p.3193-3328
Main Authors: Schmidt, Arndt W, Reddy, Kethiri R, Knölker, Hans-Joachim
Format: Article
Language:English
Subjects:
Alkaloids - chemical synthesis
Alkaloids - chemistry
Alkaloids - isolation & purification
Alkaloids - pharmacology
Benzoquinones - chemical synthesis
Carbazoles - chemical synthesis
Carbazoles - chemistry
Carbazoles - pharmacology
Chemical synthesis
Ellipticines - chemical synthesis
Evolutionary biology
Furans - chemical synthesis
Indole Alkaloids - chemical synthesis
Molecular Structure
Organic chemistry
Organic Chemistry Phenomena
Pyrroles - chemical synthesis
Quinones - chemical synthesis
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Description
Summary:A study investigated the occurrence, biogenesis and synthesis of biologically active carbazole alkaloids, which can be constructed by cycling biphenyls with an orthonitrogen substitute or diarylamines. Fischer-Borche synthesis is one avenue by which carbazoles can be prepared.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr200447s