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The prevalence of priapism in children and adolescents with sickle cell disease in Brazil
To evaluate priapism rates in individuals
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| Published in: | International journal of hematology 2012-06, Vol.95 (6), p.648-651 |
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| Main Authors: | , , , , , , |
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| cites | cdi_FETCH-LOGICAL-c455t-d8a4e4a323bc52d41cc0ae5ae09758c22f6b845c64f5a55bdb73d42dde51c1003 |
| container_end_page | 651 |
| container_issue | 6 |
| container_start_page | 648 |
| container_title | International journal of hematology |
| container_volume | 95 |
| creator | Furtado, Paulo Sampaio Costa, Milena Paiva Ribeiro do Prado Valladares, Flávia Oliveira da Silva, Leandro Lordêlo, Maurício Lyra, Isa Barroso, Ubirajara |
| description | To evaluate priapism rates in individuals |
| doi_str_mv | 10.1007/s12185-012-1083-0 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1020829481</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2688006651</sourcerecordid><originalsourceid>FETCH-LOGICAL-c455t-d8a4e4a323bc52d41cc0ae5ae09758c22f6b845c64f5a55bdb73d42dde51c1003</originalsourceid><addsrcrecordid>eNp10EFrFDEUB_BQlHatfgAvEhDBy9Qkk0xmjra0VSh4qYeehjfJGzc1m1nzdiv20zfTXbUInkLI7738-TP2WooTKYT9QFLJ1lRCqkqKtq7EAVvItjFVba1-xhaiU6YyVooj9oLoVghphbaH7EgpU3d1Yxbs5nqJfJ3xDiImh3wayy3AOtCKh8TdMkSfMXFInoOfIpLDtCH-M2yWnIL7HpE7jJH7QAiE89BphvsQX7LnI0TCV_vzmH29OL8--1Rdfbn8fPbxqnLamE3lW9CooVb14IzyWjonAA2g6KxpnVJjM7TauEaPBowZ_GBrr5X3aKQrLdTH7P1u7zpPP7ZIm34VaI4ECact9VIo0apOt7LQt__Q22mbU0n3qHTXlSqLkjvl8kSUcexLIyvIvwrq5977Xe99wf3cez-HeLPfvB1W6P9M_C66gHd7AOQgjhmSC_TXNaLTxjbFqZ2j8pS-YX4a8X-_PwCRJpmc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1020499012</pqid></control><display><type>article</type><title>The prevalence of priapism in children and adolescents with sickle cell disease in Brazil</title><source>Springer Link</source><creator>Furtado, Paulo Sampaio ; Costa, Milena Paiva ; Ribeiro do Prado Valladares, Flávia ; Oliveira da Silva, Leandro ; Lordêlo, Maurício ; Lyra, Isa ; Barroso, Ubirajara</creator><creatorcontrib>Furtado, Paulo Sampaio ; Costa, Milena Paiva ; Ribeiro do Prado Valladares, Flávia ; Oliveira da Silva, Leandro ; Lordêlo, Maurício ; Lyra, Isa ; Barroso, Ubirajara</creatorcontrib><description>To evaluate priapism rates in individuals <18 years of age with sickle cell disease (SCD) at a referral center. An evaluation was made of 599 consecutive male patients with SCD, separated according to type of hemoglobinopathy (HbSS, HbSC and HbS-β-thalassemia). Age at first episode and number of episodes were recorded. Cases of sickle cell trait were excluded. Mean age was similar in all groups. Overall, priapism occurred in 3.6 % of patients (5.6 % of those with HbSS and 1.1 % of those with HbSC;
P
= 0.01). In HbSS patients, the prevalence rate of priapism was from 3.5 (CI 95 % 0.94–13.4) when compared with patients with HbSC. No patient with β-thalassemia had priapism. Mean follow-up was 39.7 months (range 1–202 months). Since 91 % of patients with priapism had HbSS, this group was evaluated separately, revealing a rate of priapism of 1.6 % in patients <10 years and 8.3 % in those ≥10 years of age (
P
= 0.002). Regarding priapism in HbSS patients ≥10 years (8.3 %) when compared with patients <10 years (1.6 %), the prevalence rate was from 3.3 (CI 95 % 1.1–9.5). Duration of follow-up was not correlated with priapism (
P
= 0.774). Forty-seven patients were lost to follow-up. Telephone contact was successful with 14/22 patients with priapism, 50 % of whom had required hospital treatment. Most episodes (86 %) occurred at night, always during sleep. Medical interventions were required in 13 cases as follows: intravenous hydration (
n
= 4), corpora cavernosa puncture and drainage (
n
= 7) and corpus cavernosum–corpus spongiosum shunts (
n
= 2). The prevalence of priapism in children <18 years of age with SCD was 3.6 %, lower than previously reported. Prevalence was higher in HbSS patients, increasing in patients >10 years of age. Most episodes occurred at night and half of the patients required some form of urological procedure.</description><identifier>ISSN: 0925-5710</identifier><identifier>EISSN: 1865-3774</identifier><identifier>DOI: 10.1007/s12185-012-1083-0</identifier><identifier>PMID: 22539365</identifier><language>eng</language><publisher>Japan: Springer Japan</publisher><subject>Adolescent ; Anemia, Sickle Cell - complications ; Anemias. Hemoglobinopathies ; Biological and medical sciences ; Brazil - epidemiology ; Child ; Child, Preschool ; Diseases of red blood cells ; Follow-Up Studies ; Gynecology. Andrology. Obstetrics ; Hematologic and hematopoietic diseases ; Hematology ; Humans ; Infant ; Male ; Male genital diseases ; Medical sciences ; Medicine ; Medicine & Public Health ; Non tumoral diseases ; Oncology ; Original Article ; Prevalence ; Priapism - epidemiology ; Priapism - etiology</subject><ispartof>International journal of hematology, 2012-06, Vol.95 (6), p.648-651</ispartof><rights>The Japanese Society of Hematology 2012</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-d8a4e4a323bc52d41cc0ae5ae09758c22f6b845c64f5a55bdb73d42dde51c1003</citedby><cites>FETCH-LOGICAL-c455t-d8a4e4a323bc52d41cc0ae5ae09758c22f6b845c64f5a55bdb73d42dde51c1003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26094576$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22539365$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Furtado, Paulo Sampaio</creatorcontrib><creatorcontrib>Costa, Milena Paiva</creatorcontrib><creatorcontrib>Ribeiro do Prado Valladares, Flávia</creatorcontrib><creatorcontrib>Oliveira da Silva, Leandro</creatorcontrib><creatorcontrib>Lordêlo, Maurício</creatorcontrib><creatorcontrib>Lyra, Isa</creatorcontrib><creatorcontrib>Barroso, Ubirajara</creatorcontrib><title>The prevalence of priapism in children and adolescents with sickle cell disease in Brazil</title><title>International journal of hematology</title><addtitle>Int J Hematol</addtitle><addtitle>Int J Hematol</addtitle><description>To evaluate priapism rates in individuals <18 years of age with sickle cell disease (SCD) at a referral center. An evaluation was made of 599 consecutive male patients with SCD, separated according to type of hemoglobinopathy (HbSS, HbSC and HbS-β-thalassemia). Age at first episode and number of episodes were recorded. Cases of sickle cell trait were excluded. Mean age was similar in all groups. Overall, priapism occurred in 3.6 % of patients (5.6 % of those with HbSS and 1.1 % of those with HbSC;
P
= 0.01). In HbSS patients, the prevalence rate of priapism was from 3.5 (CI 95 % 0.94–13.4) when compared with patients with HbSC. No patient with β-thalassemia had priapism. Mean follow-up was 39.7 months (range 1–202 months). Since 91 % of patients with priapism had HbSS, this group was evaluated separately, revealing a rate of priapism of 1.6 % in patients <10 years and 8.3 % in those ≥10 years of age (
P
= 0.002). Regarding priapism in HbSS patients ≥10 years (8.3 %) when compared with patients <10 years (1.6 %), the prevalence rate was from 3.3 (CI 95 % 1.1–9.5). Duration of follow-up was not correlated with priapism (
P
= 0.774). Forty-seven patients were lost to follow-up. Telephone contact was successful with 14/22 patients with priapism, 50 % of whom had required hospital treatment. Most episodes (86 %) occurred at night, always during sleep. Medical interventions were required in 13 cases as follows: intravenous hydration (
n
= 4), corpora cavernosa puncture and drainage (
n
= 7) and corpus cavernosum–corpus spongiosum shunts (
n
= 2). The prevalence of priapism in children <18 years of age with SCD was 3.6 %, lower than previously reported. Prevalence was higher in HbSS patients, increasing in patients >10 years of age. Most episodes occurred at night and half of the patients required some form of urological procedure.</description><subject>Adolescent</subject><subject>Anemia, Sickle Cell - complications</subject><subject>Anemias. Hemoglobinopathies</subject><subject>Biological and medical sciences</subject><subject>Brazil - epidemiology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Diseases of red blood cells</subject><subject>Follow-Up Studies</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Hematology</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Male genital diseases</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Non tumoral diseases</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Prevalence</subject><subject>Priapism - epidemiology</subject><subject>Priapism - etiology</subject><issn>0925-5710</issn><issn>1865-3774</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp10EFrFDEUB_BQlHatfgAvEhDBy9Qkk0xmjra0VSh4qYeehjfJGzc1m1nzdiv20zfTXbUInkLI7738-TP2WooTKYT9QFLJ1lRCqkqKtq7EAVvItjFVba1-xhaiU6YyVooj9oLoVghphbaH7EgpU3d1Yxbs5nqJfJ3xDiImh3wayy3AOtCKh8TdMkSfMXFInoOfIpLDtCH-M2yWnIL7HpE7jJH7QAiE89BphvsQX7LnI0TCV_vzmH29OL8--1Rdfbn8fPbxqnLamE3lW9CooVb14IzyWjonAA2g6KxpnVJjM7TauEaPBowZ_GBrr5X3aKQrLdTH7P1u7zpPP7ZIm34VaI4ECact9VIo0apOt7LQt__Q22mbU0n3qHTXlSqLkjvl8kSUcexLIyvIvwrq5977Xe99wf3cez-HeLPfvB1W6P9M_C66gHd7AOQgjhmSC_TXNaLTxjbFqZ2j8pS-YX4a8X-_PwCRJpmc</recordid><startdate>20120601</startdate><enddate>20120601</enddate><creator>Furtado, Paulo Sampaio</creator><creator>Costa, Milena Paiva</creator><creator>Ribeiro do Prado Valladares, Flávia</creator><creator>Oliveira da Silva, Leandro</creator><creator>Lordêlo, Maurício</creator><creator>Lyra, Isa</creator><creator>Barroso, Ubirajara</creator><general>Springer Japan</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7T7</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20120601</creationdate><title>The prevalence of priapism in children and adolescents with sickle cell disease in Brazil</title><author>Furtado, Paulo Sampaio ; Costa, Milena Paiva ; Ribeiro do Prado Valladares, Flávia ; Oliveira da Silva, Leandro ; Lordêlo, Maurício ; Lyra, Isa ; Barroso, Ubirajara</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c455t-d8a4e4a323bc52d41cc0ae5ae09758c22f6b845c64f5a55bdb73d42dde51c1003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Anemia, Sickle Cell - complications</topic><topic>Anemias. Hemoglobinopathies</topic><topic>Biological and medical sciences</topic><topic>Brazil - epidemiology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Diseases of red blood cells</topic><topic>Follow-Up Studies</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Hematology</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Male genital diseases</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Non tumoral diseases</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Prevalence</topic><topic>Priapism - epidemiology</topic><topic>Priapism - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Furtado, Paulo Sampaio</creatorcontrib><creatorcontrib>Costa, Milena Paiva</creatorcontrib><creatorcontrib>Ribeiro do Prado Valladares, Flávia</creatorcontrib><creatorcontrib>Oliveira da Silva, Leandro</creatorcontrib><creatorcontrib>Lordêlo, Maurício</creatorcontrib><creatorcontrib>Lyra, Isa</creatorcontrib><creatorcontrib>Barroso, Ubirajara</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Nucleic Acids Abstracts</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Furtado, Paulo Sampaio</au><au>Costa, Milena Paiva</au><au>Ribeiro do Prado Valladares, Flávia</au><au>Oliveira da Silva, Leandro</au><au>Lordêlo, Maurício</au><au>Lyra, Isa</au><au>Barroso, Ubirajara</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prevalence of priapism in children and adolescents with sickle cell disease in Brazil</atitle><jtitle>International journal of hematology</jtitle><stitle>Int J Hematol</stitle><addtitle>Int J Hematol</addtitle><date>2012-06-01</date><risdate>2012</risdate><volume>95</volume><issue>6</issue><spage>648</spage><epage>651</epage><pages>648-651</pages><issn>0925-5710</issn><eissn>1865-3774</eissn><abstract>To evaluate priapism rates in individuals <18 years of age with sickle cell disease (SCD) at a referral center. An evaluation was made of 599 consecutive male patients with SCD, separated according to type of hemoglobinopathy (HbSS, HbSC and HbS-β-thalassemia). Age at first episode and number of episodes were recorded. Cases of sickle cell trait were excluded. Mean age was similar in all groups. Overall, priapism occurred in 3.6 % of patients (5.6 % of those with HbSS and 1.1 % of those with HbSC;
P
= 0.01). In HbSS patients, the prevalence rate of priapism was from 3.5 (CI 95 % 0.94–13.4) when compared with patients with HbSC. No patient with β-thalassemia had priapism. Mean follow-up was 39.7 months (range 1–202 months). Since 91 % of patients with priapism had HbSS, this group was evaluated separately, revealing a rate of priapism of 1.6 % in patients <10 years and 8.3 % in those ≥10 years of age (
P
= 0.002). Regarding priapism in HbSS patients ≥10 years (8.3 %) when compared with patients <10 years (1.6 %), the prevalence rate was from 3.3 (CI 95 % 1.1–9.5). Duration of follow-up was not correlated with priapism (
P
= 0.774). Forty-seven patients were lost to follow-up. Telephone contact was successful with 14/22 patients with priapism, 50 % of whom had required hospital treatment. Most episodes (86 %) occurred at night, always during sleep. Medical interventions were required in 13 cases as follows: intravenous hydration (
n
= 4), corpora cavernosa puncture and drainage (
n
= 7) and corpus cavernosum–corpus spongiosum shunts (
n
= 2). The prevalence of priapism in children <18 years of age with SCD was 3.6 %, lower than previously reported. Prevalence was higher in HbSS patients, increasing in patients >10 years of age. Most episodes occurred at night and half of the patients required some form of urological procedure.</abstract><cop>Japan</cop><pub>Springer Japan</pub><pmid>22539365</pmid><doi>10.1007/s12185-012-1083-0</doi><tpages>4</tpages></addata></record> |
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| subjects | Adolescent Anemia, Sickle Cell - complications Anemias. Hemoglobinopathies Biological and medical sciences Brazil - epidemiology Child Child, Preschool Diseases of red blood cells Follow-Up Studies Gynecology. Andrology. Obstetrics Hematologic and hematopoietic diseases Hematology Humans Infant Male Male genital diseases Medical sciences Medicine Medicine & Public Health Non tumoral diseases Oncology Original Article Prevalence Priapism - epidemiology Priapism - etiology |
| title | The prevalence of priapism in children and adolescents with sickle cell disease in Brazil |
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