The effect of movement rate and complexity on functional magnetic resonance signal change during pedaling

We used functional magnetic resonance imaging (fMRI) to record human brain activity during slow (30 RPM), fast (60 RPM), passive (30 RPM), and variable rate pedaling. Ten healthy adults participated. After identifying regions of interest, the intensity and volume of brain activation in each region w...

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Bibliographic Details
Published in:Motor control 2012-04, Vol.16 (2), p.158-175
Main Authors: Mehta, Jay P, Verber, Matthew D, Wieser, Jon A, Schmit, Brian D, Schindler-Ivens, Sheila M
Format: Article
Language:English
Subjects:
Adult
Adults
Bicycling
Brain
Brain Mapping
Cerebellum - physiology
Female
Frontal Lobe - physiology
Functional Neuroimaging
Health
Humans
Legs
Locomotion - physiology
Magnetic Resonance Imaging
Male
Middle Aged
Motor control
Motor Cortex - physiology
Movement
NMR
Nuclear magnetic resonance
Parietal Lobe - physiology
Scanning
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Description
Summary:We used functional magnetic resonance imaging (fMRI) to record human brain activity during slow (30 RPM), fast (60 RPM), passive (30 RPM), and variable rate pedaling. Ten healthy adults participated. After identifying regions of interest, the intensity and volume of brain activation in each region was calculated and compared across conditions (p < .05). Results showed that the primary sensory and motor cortices (S1, M1), supplementary motor area (SMA), and cerebellum (Cb) were active during pedaling. The intensity of activity in these areas increased with increasing pedaling rate and complexity. The Cb was the only brain region that showed significantly lower activity during passive as compared with active pedaling. We conclude that M1, S1, SMA, and Cb have a role in modifying continuous, bilateral, multijoint lower extremity movements. Much of this brain activity may be driven by sensory signals from the moving limbs.
ISSN:1087-1640
1543-2696
DOI:10.1123/mcj.16.2.158