Retrospective clinical and laboratory evaluation of children with brucellosis

Background:  Acute brucellosis is a zoonotic disease seen in childhood, with non‐specific complaints and clinical findings that can affect the locomotor, gastrointestinal, genitourinary, hematologic, cardiovascular, respiratory, and central nervous systems. Particularly in endemic regions, it occurs...

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Published in:Pediatrics international 2012-04, Vol.54 (2), p.215-218
Main Authors: Okur, Mesut, Erbey, Fatih, Bektaş, Mehmet Selçuk, kaya, Avni, Doğan, Murat, Acar, Mehmet Nuri, Uzun, Hakan
Format: Article
Language:English
Subjects:
Adolescent
Anemia - etiology
Brucellosis
Brucellosis - complications
Brucellosis - diagnosis
Brucellosis - drug therapy
Brucellosis - transmission
Child
Child, Preschool
childhood
Childrens health
clinical and laboratory findings
Female
Humans
Leukopenia - etiology
Male
Pancytopenia - etiology
Retrospective Studies
Thrombocytopenia - etiology
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Summary:Background:  Acute brucellosis is a zoonotic disease seen in childhood, with non‐specific complaints and clinical findings that can affect the locomotor, gastrointestinal, genitourinary, hematologic, cardiovascular, respiratory, and central nervous systems. Particularly in endemic regions, it occurs as a result of consumption of unpasteurized milk and dairy products. In this study, clinical and laboratory findings of children with acute brucellosis are presented. Methods:  Data for 147 patients, aged 2–16 years, were evaluated retrospectively. Results:  The most frequent complaints and clinical findings were abdominal pain and fever. Other complaints and clinical findings included arthralgia, myalgia, loss of appetite, weakness, sweating, fatigue, headache, arthritis, hepatomegaly, and splenomegaly. Anemia was the most frequent hematological abnormality detected; other abnormalities included leukopenia, thrombocytopenia, and pancytopenia. Conclusion:  Childhood brucellosis can cause non‐specific complaints and particularly anemia and leukopenia as hematological abnormalities. It is easily treated, however, with appropriate antibiotics.
ISSN:1328-8067
1442-200X
DOI:10.1111/j.1442-200X.2011.03558.x