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A randomised, single-blind, dose-range study to assess the immunogenicity and safety of a cell-culture-derived A/H1N1 influenza vaccine in adult and elderly populations
Highlights ► One dose of cell-culture-derived, pandemic influenza vaccine adequate for adults. ► Two doses required for the elderly. Adjuvanted vaccine well tolerated in all subjects. ► Rapid production by cell-culture helps to meet global demand for pandemic vaccines.
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| Published in: | Vaccine 2012-07, Vol.30 (32), p.4820-4827 |
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| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c472t-341310ff99d913f609e464fa39b05635a29f5406a94bc61be79047ae9f1ac4183 |
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| cites | cdi_FETCH-LOGICAL-c472t-341310ff99d913f609e464fa39b05635a29f5406a94bc61be79047ae9f1ac4183 |
| container_end_page | 4827 |
| container_issue | 32 |
| container_start_page | 4820 |
| container_title | Vaccine |
| container_volume | 30 |
| creator | Hatz, Christoph Cramer, Jakob P Vertruyen, André Schwarz, Tino F von Sonnenburg, Frank Borkowski, Astrid Lattanzi, Maria Hilbert, Anne Katrin Cioppa, Giovanni Della Leroux-Roels, Geert |
| description | Highlights ► One dose of cell-culture-derived, pandemic influenza vaccine adequate for adults. ► Two doses required for the elderly. Adjuvanted vaccine well tolerated in all subjects. ► Rapid production by cell-culture helps to meet global demand for pandemic vaccines. |
| doi_str_mv | 10.1016/j.vaccine.2012.05.013 |
| format | article |
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Adjuvanted vaccine well tolerated in all subjects. ► Rapid production by cell-culture helps to meet global demand for pandemic vaccines.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>22626675</pmid><doi>10.1016/j.vaccine.2012.05.013</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0264-410X |
| ispartof | Vaccine, 2012-07, Vol.30 (32), p.4820-4827 |
| issn | 0264-410X 1873-2518 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1021982671 |
| source | ScienceDirect Journals |
| subjects | Adjuvant adjuvants Adjuvants, Immunologic - administration & dosage Adolescent Adult Aged Allergy and Immunology Antibodies, Viral - blood Antigens cell culture Cell Culture Techniques Clinical trials diagnostic techniques elderly Female Fever H1N1 Hemagglutination Inhibition Tests Humans immune response Immunization, Secondary Immunogenicity Influenza Influenza A Virus, H1N1 Subtype Influenza Vaccines - adverse effects Influenza Vaccines - biosynthesis Influenza Vaccines - immunology Influenza, Human - prevention & control Male MF59 Middle Aged Pandemic Pandemics Polysorbates - administration & dosage secondary immunization Single-Blind Method Squalene - administration & dosage Swine flu vaccination Vaccines Young Adult |
| title | A randomised, single-blind, dose-range study to assess the immunogenicity and safety of a cell-culture-derived A/H1N1 influenza vaccine in adult and elderly populations |
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