Mean Platelet Volume Has a Prognostic Value in Patients With Coronary Artery Ectasia

The aim of this study was to investigate the prognostic role of mean platelet volume (MPV) in patients with coronary artery ectasia (CAE). The baseline MPV values of 258 patients with CAE were screened. The mean time of follow-up was 49 ± 21 months for major adverse cardiac events (MACEs) defined as...

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Bibliographic Details
Published in:Clinical and applied thrombosis/hemostasis 2012-07, Vol.18 (4), p.387-392
Main Authors: Varol, Ercan, Uysal, Bayram Ali, Dogan, Abdullah, Ozaydin, Mehmet, Erdogan, Dogan
Format: Article
Language:English
Subjects:
Adult
Aged
Blood Platelets
Coronary Artery Disease - blood
Coronary Artery Disease - complications
Coronary Artery Disease - diagnosis
Coronary Artery Disease - mortality
Coronary Vessels
Death
Dilatation, Pathologic
Electrocardiography
Female
Follow-Up Studies
Humans
Male
Middle Aged
Myocardial Infarction - blood
Myocardial Infarction - diagnosis
Myocardial Infarction - etiology
Myocardial Infarction - mortality
Prognosis
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Summary:The aim of this study was to investigate the prognostic role of mean platelet volume (MPV) in patients with coronary artery ectasia (CAE). The baseline MPV values of 258 patients with CAE were screened. The mean time of follow-up was 49 ± 21 months for major adverse cardiac events (MACEs) defined as the combination of cardiac death, nonfatal myocardial infarction (MI), rehospitalization due to cardiac disorders, and readmission due to chest pain. During follow-up period, 63 (24%) MACEs developed. There were 4 (2%) cardiovascular deaths, 0 nonfatal MI, 14 (5%) rehospitalization, and 45 (17%) readmission. Mean platelet volume values were significantly higher in patients with CAE with MACEs than in patients with CAE without MACEs (9.5 ± 1.2 fL vs 8.9 ± 1.1 fL, respectively, P = .002). The rate of MACE was higher in CAE patients with MPV of >9 fL than those with MVP of ≤9 fL (33% vs. 15%, P = .001). Mean platelet volume has a prognostic value for MACEs in patients with CAE.
ISSN:1076-0296
1938-2723
DOI:10.1177/1076029611427441