Properties of arsenic sulphide As₄S₄ nanoparticles prepared by high-energy milling

In this study, the nanosized arsenic sulphide As₄S₄ particles have been prepared by mechanical activation in a planetary mill. The bulk and surface properties of the milled particles were characterized by XRD and XPS methods as well as by surface area and particle size distribution measurements. For...

Full description

Saved in:
Bibliographic Details
Published in:Powder technology 2011, Vol.211 (2-3), p.232-236
Main Authors: Baláž, Peter, Nguyen, Anh V, Fabián, Martin, Cholujová, Danka, Pastorek, Michal, Sedlák, Ján, Bujňáková, Zdenka
Format: Article
Language:English
Subjects:
Applied sciences
Arsenic
bioactive properties
Biological
Cancer
Chemical engineering
Crystallization, leaching, miscellaneous separations
Drugs
Exact sciences and technology
Grinding
Mechanical activation
Mechanical alloying
milling
Miscellaneous
myeloma
nanoparticles
Nanostructure
neoplasm cells
particle size distribution
Solid-solid systems
Sulfides
surface area
viability
X-ray diffraction
X-ray photoelectron spectroscopy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this study, the nanosized arsenic sulphide As₄S₄ particles have been prepared by mechanical activation in a planetary mill. The bulk and surface properties of the milled particles were characterized by XRD and XPS methods as well as by surface area and particle size distribution measurements. For assessment of arsenic sulphide biological activity, the viability tests of multiple myeloma cancer cells have been applied. The obtained results show the arsenic sulphide nanoparticles properly milled and modified by mechanical activation can be valuated as a potential drug for cancer treatment.
ISSN:0032-5910
1873-328X
DOI:10.1016/j.powtec.2011.04.027