Immunological differences in the global release of the major cat allergen Fel d 1 are influenced by sex and behaviour

The biological function of Fel d 1, the major cat allergen released in the environment, is still unclear despite studies suggesting a putative role in chemical communication. Structural and immunological polymorphisms of Fel d 1 have been described. This study examined how Fel d 1 immunological poly...

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Bibliographic Details
Published in:The veterinary journal (1997) 2012-07, Vol.193 (1), p.162-167
Main Authors: Bienboire-Frosini, Cécile, Cozzi, Alessandro, Lafont-Lecuelle, Céline, Vervloet, Daniel, Ronin, Catherine, Pageat, Patrick
Format: Article
Language:English
Subjects:
Aggression
allergens
Allergens - immunology
Animals
Antibodies, Monoclonal - immunology
Behaviour
Cat
cats
Cats - immunology
Cats - physiology
Enzyme-Linked Immunosorbent Assay
Fel d 1
Female
females
Glycoproteins - immunology
Male
males
Polymorphism
Sex
Sex Distribution
Social Behavior
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Summary:The biological function of Fel d 1, the major cat allergen released in the environment, is still unclear despite studies suggesting a putative role in chemical communication. Structural and immunological polymorphisms of Fel d 1 have been described. This study examined how Fel d 1 immunological polymorphism may have a physiological origin by estimating a potential relationship with the sex of cats and cat–human interactions. Samples from bath washes of 21 cats were screened to study antibody binding to Fel d 1 using an ELISA. Personality and Tolerance Handling scores were used to assess the behaviour of the cats. In the washes, Fel d 1 concentrations were significantly lower in females than in males (P
ISSN:1090-0233
1532-2971
DOI:10.1016/j.tvjl.2011.09.031