A case of Helicobacter pylori infection complicated with gastric cancer, gastric mucosa‐associated lymphoid tissue lymphoma, and idiopathic thrombocytopenic purpura successfully treated with laparoscopy‐assisted total gastrectomy and splenectomy

Helicobacter pylori infection plays a key role in the pathogenesis of H. pylori‐associated diseases, including gastroduodenal and non‐gastroduodenal diseases. A 71‐year‐old man was evaluated for a positive fecal occult blood test by upper gastrointestinal endoscopy, which revealed H. pylori infectio...

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Bibliographic Details
Published in:Asian journal of endoscopic surgery 2011-02, Vol.4 (1), p.32-35
Main Authors: Hamabe, A, Omori, T, Oyama, T, Akamatsu, H, Yoshidome, K, Tori, M, Ueshima, S, Tsujimoto, M, Nishida, T
Format: Article
Language:English
Subjects:
Adenocarcinoma - complications
Adenocarcinoma - surgery
Aged
Gastrectomy
Helicobacter infections
Helicobacter Infections - complications
Helicobacter pylori
Humans
laparoscopic surgery
Laparoscopy
Lymphoma, B-Cell, Marginal Zone - complications
Lymphoma, B-Cell, Marginal Zone - surgery
Male
Purpura, Thrombocytopenic, Idiopathic - complications
Purpura, Thrombocytopenic, Idiopathic - surgery
Splenectomy
Stomach Neoplasms - complications
Stomach Neoplasms - surgery
Treatment Outcome
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Summary:Helicobacter pylori infection plays a key role in the pathogenesis of H. pylori‐associated diseases, including gastroduodenal and non‐gastroduodenal diseases. A 71‐year‐old man was evaluated for a positive fecal occult blood test by upper gastrointestinal endoscopy, which revealed H. pylori infection, two adenocarcinomas and two gastric mucosa‐associated lymphoid tissue lymphomas. Hematological examination revealed low platelet‐count, elevated platelet‐associated immunoglobulin G and anti‐H. pylori immunoglobulin G antibodies. We diagnosed H. pylori infection complicated by simultaneous occurrence of gastric cancer, gastric mucosa‐associated lymphoid tissue lymphoma, and idiopathic thrombocytopenic purpura. These diseases were successfully treated with laparoscopy‐assisted total gastrectomy and splenectomy, and there was no evidence of recurrence for about 2 years. This is the first reported case of H. pylori infection complicated by these three diseases and cured with laparoscopic surgery.
ISSN:1758-5902
1758-5910
DOI:10.1111/j.1758-5910.2010.00067.x