Low testosterone levels as an independent predictor of mortality in men with chronic liver disease

Objective To examine the prevalence and prognostic implications of low serum testosterone levels in men with chronic liver disease. Design We conducted an observational study at a tertiary referral centre. Patients and measurements Baseline serum testosterone was measured in 171 men presenting to th...

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Bibliographic Details
Published in:Clinical endocrinology (Oxford) 2012-08, Vol.77 (2), p.323-328
Main Authors: Grossmann, Mathis, Hoermann, Rudolf, Gani, Linsey, Chan, Irene, Cheung, Ada, Gow, Paul J, Li, Angela, Zajac, Jeffrey D., Angus, Peter
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chronic Disease - mortality
Endocrinopathies
Epidemiology
Fundamental and applied biological sciences. Psychology
General aspects
Humans
Liver Diseases - blood
Liver Diseases - mortality
Male
Medical sciences
Middle Aged
Public health. Hygiene
Public health. Hygiene-occupational medicine
Testosterone - blood
Vertebrates: endocrinology
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Summary:Objective To examine the prevalence and prognostic implications of low serum testosterone levels in men with chronic liver disease. Design We conducted an observational study at a tertiary referral centre. Patients and measurements Baseline serum testosterone was measured in 171 men presenting to the Victorian Liver Transplant Unit for liver transplant evaluation. Patients were followed up to liver transplant or death. Results Sixty‐one per cent of men had a low total testosterone level (TT,
ISSN:0300-0664
1365-2265
DOI:10.1111/j.1365-2265.2012.04347.x