Prognostic studies of canine and feline mammary tumours: The need for standardized procedures

For several years, veterinary oncologists have been struggling with the prognosis of mammary tumours in dogs and cats. Translation of tumour characteristics into prognostic information is an invaluable tool for the use of the most appropriate therapies, as well as for planning innovative therapeutic...

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Bibliographic Details
Published in:The veterinary journal (1997) 2012-07, Vol.193 (1), p.24-31
Main Authors: Matos, A.J.F., Baptista, C.S., Gärtner, M.F., Rutteman, G.R.
Format: Article
Language:English
Subjects:
Animals
Canine
Cat Diseases - diagnosis
Cat Diseases - pathology
Cats
Comparative oncology
Dog Diseases - diagnosis
Dog Diseases - pathology
Dogs
Feline
Female
Mammary Neoplasms, Animal - diagnosis
Mammary Neoplasms, Animal - pathology
Mammary tumours
Practice Guidelines as Topic
Prognosis
Prognostic studies
Reproducibility of Results
Standardization
Veterinary Medicine - methods
Veterinary Medicine - standards
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Summary:For several years, veterinary oncologists have been struggling with the prognosis of mammary tumours in dogs and cats. Translation of tumour characteristics into prognostic information is an invaluable tool for the use of the most appropriate therapies, as well as for planning innovative therapeutic trials. Moreover, canine and feline spontaneous mammary gland tumours are good models for the study of human breast cancer. Collecting and interpreting information regarding the prognosis of canine and feline mammary tumours is difficult due to the fact that different methods have been applied to study various components and characteristics. This review identifies some of the challenges of prognostic studies of spontaneous canine and feline mammary tumours and suggests standardized procedures to overcome these challenges and facilitate reproducibility and assessment of results.
ISSN:1090-0233
1532-2971
DOI:10.1016/j.tvjl.2011.12.019