Assessment of atherosclerotic plaques at coronary bifurcations with multidetector computed tomography angiography and intravascular ultrasound-virtual histology

We evaluated the distribution and composition of atherosclerotic plaques at bifurcations with intravascular ultrasound-virtual histology (IVUS-VH) and multidetector computed tomography (MDCT) in relation to the bifurcation angle (BA). In 33 patients (age 63±11 years, 79% male) imaged with IVUS-VH an...

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Bibliographic Details
Published in:European heart journal cardiovascular imaging 2012-08, Vol.13 (8), p.635-642
Main Authors: Papadopoulou, Stella-Lida, Brugaletta, Salvatore, Garcia-Garcia, Hector M, Rossi, Alexia, Girasis, Chrysafios, Dharampal, Anoeshka S, Neefjes, Lisan A, Ligthart, Jurgen, Nieman, Koen, Krestin, Gabriel P, Serruys, Patrick W, de Feyter, Pim J
Format: Article
Language:English
Subjects:
Cardiac-Gated Imaging Techniques - methods
Contrast Media
Coronary Angiography
Coronary Artery Disease - diagnostic imaging
Female
Humans
Iohexol - analogs & derivatives
Male
Middle Aged
Phenotype
Plaque, Atherosclerotic - diagnostic imaging
Risk Factors
Statistics, Nonparametric
Tomography, X-Ray Computed - methods
Ultrasonography, Interventional
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Summary:We evaluated the distribution and composition of atherosclerotic plaques at bifurcations with intravascular ultrasound-virtual histology (IVUS-VH) and multidetector computed tomography (MDCT) in relation to the bifurcation angle (BA). In 33 patients (age 63±11 years, 79% male) imaged with IVUS-VH and MDCT, 33 bifurcations were matched and studied. The analysed main vessel was divided into a 5 mm proximal segment, the in-bifurcation segment, and a 5 mm distal segment. Plaque contours were manually traced on MDCT and IVUS-VH. Plaques with >10% confluent necrotic core and
ISSN:2047-2404
2047-2412
DOI:10.1093/ehjci/jes083