Prevalence and Antimicrobial Susceptibility Pattern of Methicillin Resistance Staphylococcus in a Sudanese Surgical Ward

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is important nosocomial pathogen. Aim: In this paper, we determined the prevalence and the antibiotic susceptibility pattern of (MRSA) in a Sudanese surgical ward. Method: A total of 200 post-operative surgical specimens were collected f...

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Bibliographic Details
Published in:Pharmacology & pharmacy 2012, Vol.3 (1), p.103-108
Main Authors: Kheder, Salah Ibrahim, Ali, Nagla A., Fathelrahman, Ahmed Ibrahim
Format: Article
Language:English
Subjects:
Amikacin
Antibiotics
Antimicrobial agents
Cross-resistance
Drug resistance
Gastrointestinal tract
Hospitals
Methicillin
Ofloxacin
Pathogens
Staphylococcus aureus
Vancomycin
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Summary:Background: Methicillin-resistant Staphylococcus aureus (MRSA) is important nosocomial pathogen. Aim: In this paper, we determined the prevalence and the antibiotic susceptibility pattern of (MRSA) in a Sudanese surgical ward. Method: A total of 200 post-operative surgical specimens were collected from patients hospitalized in gastrointestinal tract (GIT) surgical ward in Ibn Sina hospital, Khartoum, Sudan and were subjected to MRSA screening and sensitivity test. Key Findings: Out of 35 strains of Staphylococcus aureus isolated from surgical samples, 25 (71.4%) were found to be MRSA. Almost all MRSA strains were resistant to Methicillin, 96% to Ofloxacin, 92% to Pencillin G, 24% to Amikacin and 4% to Vancomycin. Cross-resistance was obviously detected. Conclusion: The present study detected alarming levels of S. aureus (MRSA) isolates, at the same time presence of high cross-resistance to other antibiotics.
ISSN:2157-9423
2157-9431
DOI:10.4236/pp.2012.31015