Crystal structure of PqqB from Pseudomonas putida at 2.2 Aa resolution

Pyrroloquinoline quinone (PQQ) is an important redox-active cofactor for many bacterial dehy- drogenases. It's biosynthetic pathway involves six or seven genes, one of which is pqqB. For-mer studies indicated that the protein encoded by pqqB, namely PqqB, functions as a PQQ transporter. Here we...

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Bibliographic Details
Published in:Journal of biophysical chemistry 2012-05, Vol.3 (2), p.206-206
Main Authors: Metlitzky, Moritz, Puehringer, Sandra, Fisher, Stuart J
Format: Article
Language:English
Subjects:
Cofactors
Crystal structure
Pseudomonas putida
pyrroloquinoline quinone
Online Access:Get full text
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Summary:Pyrroloquinoline quinone (PQQ) is an important redox-active cofactor for many bacterial dehy- drogenases. It's biosynthetic pathway involves six or seven genes, one of which is pqqB. For-mer studies indicated that the protein encoded by pqqB, namely PqqB, functions as a PQQ transporter. Here we report the crystal structure of PqqB from Pseudomonas putida at 2.2 Aa resolution together with functional studies to verify this theory.
ISSN:2153-036X
2153-0378