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A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction
Introduction and hypothesis The aim of this manuscript was to provide a systematic literature review of clinical trial evidence for a range of electrical stimulation therapies in the treatment of lower urinary tract symptoms (LUTS). Methods The databases MEDLINE, BIOSIS Previews, Inside Conferences,...
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Published in: | International Urogynecology Journal 2012-08, Vol.23 (8), p.993-1005 |
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description | Introduction and hypothesis
The aim of this manuscript was to provide a systematic literature review of clinical trial evidence for a range of electrical stimulation therapies in the treatment of lower urinary tract symptoms (LUTS).
Methods
The databases MEDLINE, BIOSIS Previews, Inside Conferences, and EMBASE were searched. Original clinical studies with greater than 15 subjects were included.
Results
Seventy-three studies were included, representing implanted sacral nerve stimulation (SNS), percutaneous posterior tibial nerve stimulation (PTNS), and transcutaneous electrical stimulation (TENS) therapy modalities.
Conclusions
Median mean reductions in incontinence episodes and voiding frequency were similar for implanted SNS and PTNS. However, long-term follow-up data to validate the sustained benefit of PTNS are lacking. Despite a substantial body of research devoted to SNS validation, it is not possible to definitively define the appropriate role of this therapy owing largely to study design flaws that inhibited rigorous intention to treat analyses for the majority of these studies. |
doi_str_mv | 10.1007/s00192-012-1691-5 |
format | article |
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The aim of this manuscript was to provide a systematic literature review of clinical trial evidence for a range of electrical stimulation therapies in the treatment of lower urinary tract symptoms (LUTS).
Methods
The databases MEDLINE, BIOSIS Previews, Inside Conferences, and EMBASE were searched. Original clinical studies with greater than 15 subjects were included.
Results
Seventy-three studies were included, representing implanted sacral nerve stimulation (SNS), percutaneous posterior tibial nerve stimulation (PTNS), and transcutaneous electrical stimulation (TENS) therapy modalities.
Conclusions
Median mean reductions in incontinence episodes and voiding frequency were similar for implanted SNS and PTNS. However, long-term follow-up data to validate the sustained benefit of PTNS are lacking. Despite a substantial body of research devoted to SNS validation, it is not possible to definitively define the appropriate role of this therapy owing largely to study design flaws that inhibited rigorous intention to treat analyses for the majority of these studies.</description><identifier>ISSN: 0937-3462</identifier><identifier>EISSN: 1433-3023</identifier><identifier>DOI: 10.1007/s00192-012-1691-5</identifier><identifier>PMID: 22426872</identifier><language>eng</language><publisher>London: Springer-Verlag</publisher><subject>Electric Stimulation Therapy - methods ; Gynecology ; Humans ; Incidence ; Lower Urinary Tract Symptoms - therapy ; Medicine ; Medicine & Public Health ; Review Article ; Treatment Outcome ; Urinary Incontinence - epidemiology ; Urology</subject><ispartof>International Urogynecology Journal, 2012-08, Vol.23 (8), p.993-1005</ispartof><rights>The International Urogynecological Association 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-1ef995a7a3b5b41e44106669514239b97a6165e2d47d02452ac184f11e1bfe3</citedby><cites>FETCH-LOGICAL-c372t-1ef995a7a3b5b41e44106669514239b97a6165e2d47d02452ac184f11e1bfe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22426872$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Monga, Ash K.</creatorcontrib><creatorcontrib>Tracey, Michael R.</creatorcontrib><creatorcontrib>Subbaroyan, Jeyakumar</creatorcontrib><title>A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction</title><title>International Urogynecology Journal</title><addtitle>Int Urogynecol J</addtitle><addtitle>Int Urogynecol J</addtitle><description>Introduction and hypothesis
The aim of this manuscript was to provide a systematic literature review of clinical trial evidence for a range of electrical stimulation therapies in the treatment of lower urinary tract symptoms (LUTS).
Methods
The databases MEDLINE, BIOSIS Previews, Inside Conferences, and EMBASE were searched. Original clinical studies with greater than 15 subjects were included.
Results
Seventy-three studies were included, representing implanted sacral nerve stimulation (SNS), percutaneous posterior tibial nerve stimulation (PTNS), and transcutaneous electrical stimulation (TENS) therapy modalities.
Conclusions
Median mean reductions in incontinence episodes and voiding frequency were similar for implanted SNS and PTNS. However, long-term follow-up data to validate the sustained benefit of PTNS are lacking. Despite a substantial body of research devoted to SNS validation, it is not possible to definitively define the appropriate role of this therapy owing largely to study design flaws that inhibited rigorous intention to treat analyses for the majority of these studies.</description><subject>Electric Stimulation Therapy - methods</subject><subject>Gynecology</subject><subject>Humans</subject><subject>Incidence</subject><subject>Lower Urinary Tract Symptoms - therapy</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Review Article</subject><subject>Treatment Outcome</subject><subject>Urinary Incontinence - epidemiology</subject><subject>Urology</subject><issn>0937-3462</issn><issn>1433-3023</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp1kUlLBDEQhYMoOi4_wIsEvHhpTWVrcxRxgwEPem_S6WqJ9KJJWpl_b5oZRQRPBVXfe5XUI-QY2DkwVl5ExsDwggEvQBso1BZZgBSiEIyLbbJgRpSFkJrvkf0YXxljkim2S_Y4l1xflnxBwhWNq5iwt8k7GvDD4ycdW-o6P3hnOxrT1HiMcw87dClsur6fuqwZB9qOgaaANvU4pJnrxk8MdAp-sGGVR9Yl2qxiOw1uFhySndZ2EY829YA83d48X98Xy8e7h-urZeFEyVMB2BqjbGlFrWoJKCUwrbVRILkwtSmtBq2QN7JsGJeKWweXsgVAqFsUB-Rs7foWxvcJY6p6Hx12nR1wnGIFWWOENEpl9PQP-jpOYchvm6m8UyhdZgrWlAtjjAHb6i34Pv8wQ9UcR7WOo8pxVHMc1ex8snGe6h6bH8X3_TPA10DMo-EFw-_V_7l-Aamdldo</recordid><startdate>20120801</startdate><enddate>20120801</enddate><creator>Monga, Ash K.</creator><creator>Tracey, Michael R.</creator><creator>Subbaroyan, Jeyakumar</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20120801</creationdate><title>A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction</title><author>Monga, Ash K. ; Tracey, Michael R. ; Subbaroyan, Jeyakumar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-1ef995a7a3b5b41e44106669514239b97a6165e2d47d02452ac184f11e1bfe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Electric Stimulation Therapy - methods</topic><topic>Gynecology</topic><topic>Humans</topic><topic>Incidence</topic><topic>Lower Urinary Tract Symptoms - therapy</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Review Article</topic><topic>Treatment Outcome</topic><topic>Urinary Incontinence - epidemiology</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Monga, Ash K.</creatorcontrib><creatorcontrib>Tracey, Michael R.</creatorcontrib><creatorcontrib>Subbaroyan, Jeyakumar</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>International Urogynecology Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Monga, Ash K.</au><au>Tracey, Michael R.</au><au>Subbaroyan, Jeyakumar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction</atitle><jtitle>International Urogynecology Journal</jtitle><stitle>Int Urogynecol J</stitle><addtitle>Int Urogynecol J</addtitle><date>2012-08-01</date><risdate>2012</risdate><volume>23</volume><issue>8</issue><spage>993</spage><epage>1005</epage><pages>993-1005</pages><issn>0937-3462</issn><eissn>1433-3023</eissn><abstract>Introduction and hypothesis
The aim of this manuscript was to provide a systematic literature review of clinical trial evidence for a range of electrical stimulation therapies in the treatment of lower urinary tract symptoms (LUTS).
Methods
The databases MEDLINE, BIOSIS Previews, Inside Conferences, and EMBASE were searched. Original clinical studies with greater than 15 subjects were included.
Results
Seventy-three studies were included, representing implanted sacral nerve stimulation (SNS), percutaneous posterior tibial nerve stimulation (PTNS), and transcutaneous electrical stimulation (TENS) therapy modalities.
Conclusions
Median mean reductions in incontinence episodes and voiding frequency were similar for implanted SNS and PTNS. However, long-term follow-up data to validate the sustained benefit of PTNS are lacking. Despite a substantial body of research devoted to SNS validation, it is not possible to definitively define the appropriate role of this therapy owing largely to study design flaws that inhibited rigorous intention to treat analyses for the majority of these studies.</abstract><cop>London</cop><pub>Springer-Verlag</pub><pmid>22426872</pmid><doi>10.1007/s00192-012-1691-5</doi><tpages>13</tpages></addata></record> |
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source | Springer Nature |
subjects | Electric Stimulation Therapy - methods Gynecology Humans Incidence Lower Urinary Tract Symptoms - therapy Medicine Medicine & Public Health Review Article Treatment Outcome Urinary Incontinence - epidemiology Urology |
title | A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction |
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